Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTYAWV0)

• DTT Name: Plasmodium Acetyl-CoA carboxylase 1 (Malaria ACC1) DTT Info
• Gene Name: Malaria ACC1

Molecule-Related Drug & Molecule List

6 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
A-80040	DML20N9	Discovery agent	N.A.	Investigative	[1]
AC-8632	DM09BJ4	Parkinson disease	8A00.0	Investigative	[2]
Clodinafop	DMALRU9	Discovery agent	N.A.	Investigative	[3]
CP-640186	DMO0PS9	Discovery agent	N.A.	Investigative	[4]
Haloxyfop	DM5SULN	Discovery agent	N.A.	Investigative	[3]
Quizalofop	DM9KMEI	Discovery agent	N.A.	Investigative	[3]

References

• [1] Synthesis and structure-activity relationships of N-{3-[2-(4-alkoxyphenoxy)thiazol-5-yl]-1- methylprop-2-ynyl}carboxy derivatives as selective acet... J Med Chem. 2006 Jun 29;49(13):3770-3.
• [2] Reduced food intake and body weight in mice treated with fatty acid synthase inhibitors. Science. 2000 Jun 30;288(5475):2379-81.
• [3] The apicoplast as an antimalarial drug target. Drug Resist Updat. 2001 Jun;4(3):145-51.
• [4] Discovery of small molecule isozyme non-specific inhibitors of mammalian acetyl-CoA carboxylase 1 and 2. Bioorg Med Chem Lett. 2010 Apr 1;20(7):2383-8.