General Information of DTT (ID: TTYG6BU)

DTT Name Aggrecanase-1 (ADAMTS4) DTT Info
Gene Name ADAMTS4

Molecule-Related Drug & Molecule List

Molecule-Related Drug List
Molecule Type:
DTT
DTP
DME
Drug Status:
Discontinued Drug(s)
Patented Agent(s)
Investigative Drug(s)
3 Patented Agent(s) Transported by This DTP
Drug Name Drug ID Indication ICD 11 Highest Status REF
1607004-34-1 DMM2N4T N. A. N. A. Patented [1]
US9206139, 4 DM3NE8J N. A. N. A. Patented [1]
US9206139, 5 DMB4JS7 N. A. N. A. Patented [1]
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1 Discontinued Drug(s) Transported by This DTP
Drug Name Drug ID Indication ICD 11 Highest Status REF
SC-44463 DMBPNKT N. A. N. A. Terminated [2]
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2 Investigative Drug(s) Transported by This DTP
Drug Name Drug ID Indication ICD 11 Highest Status REF
(R)-2-(biphenyl-4-sulfonylamino)-propionic acid DM16JFS Discovery agent N.A. Investigative [3]
MMI270 DM38N2K Discovery agent N.A. Investigative [3]
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Molecule Interaction Atlas

References

1 Aggrecanase inhibitors. US9206139.
2 Design and synthesis of a series of (2R)-N(4)-hydroxy-2-(3-hydroxybenzyl)-N(1)- [(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]butanediamide derivati... J Med Chem. 2001 Oct 11;44(21):3347-50.
3 Synthesis and biological evaluation of biphenylsulfonamide carboxylate aggrecanase-1 inhibitors. Bioorg Med Chem Lett. 2006 Jan 15;16(2):311-6.