General Information of DTT (ID: TTYGQ8A)

DTT Name Dual-specificity tyrosine-phosphorylation regulated kinase 1B (DYRK1B) DTT Info
Gene Name DYRK1B

Molecule-Related Drug & Molecule List

Molecule-Related Drug List
Molecule Type:
DTT
DTP
DME
Drug Status:
Patented Agent(s)
Investigative Drug(s)
18 Patented Agent(s) Transported by This DTP
Drug Name Drug ID Indication ICD 11 Highest Status REF
PMID28766366-Compound-Scheme14BINDY DMBQ0RN N. A. N. A. Patented [1]
PMID28766366-Compound-Scheme21Left DMWTRUK N. A. N. A. Patented [1]
PMID28766366-Compound-Scheme21Right DMF3X40 N. A. N. A. Patented [1]
PMID28766366-Compound-Scheme25-2 DM7OGWH N. A. N. A. Patented [1]
PMID28766366-Compound-Scheme25-3 DMGVT5Y N. A. N. A. Patented [1]
PMID28766366-Compound-Scheme25-4 DMOD9BY N. A. N. A. Patented [1]
PMID28766366-Compound-Scheme2WO2012/098065bottom DMO4Q95 N. A. N. A. Patented [1]
PMID28766366-Compound-Scheme2WO2012/098065upper DMVJDRI N. A. N. A. Patented [1]
PMID28766366-Compound-Scheme4Bottom DMDXIU9 N. A. N. A. Patented [1]
PMID28766366-Compound-Scheme4Upper DMPH4JV N. A. N. A. Patented [1]
PMID28766366-Compound-Scheme5 DMO6KZ5 N. A. N. A. Patented [1]
PMID28766366-Compound-Scheme7WO2012/098070bottom DMQV6R0 N. A. N. A. Patented [1]
PMID28766366-Compound-Scheme7WO2012/098070upper DMGAQR5 N. A. N. A. Patented [1]
PMID28766366-Compound-Scheme9EHT1610 DMMZGC8 N. A. N. A. Patented [1]
PMID28766366-Compound-Scheme9EHT3356 DMVBPML N. A. N. A. Patented [1]
PMID28766366-Compound-Scheme9EHT5372 DM0O18N N. A. N. A. Patented [1]
PMID28766366-Compound-Scheme9EHT6840 DMVY6PX N. A. N. A. Patented [1]
PMID28766366-Compound-Scheme9EHT9851 DM7RPKM N. A. N. A. Patented [1]
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⏷ Show the Full List of 18 Patented Agent(s)
3 Investigative Drug(s) Transported by This DTP
Drug Name Drug ID Indication ICD 11 Highest Status REF
PMID23642479C17 DM4JWMA Discovery agent N.A. Investigative [2]
PMID24900699C68 DM2V4MJ Discovery agent N.A. Investigative [3]
WO2013026806C72 DM21WOP Discovery agent N.A. Investigative [4]
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Molecule Interaction Atlas

References

1 Dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A) inhibitors: a survey of recent patent literature.Expert Opin Ther Pat. 2017 Nov;27(11):1183-1199.
2 Small-molecule pyrimidine inhibitors of the cdc2-like (Clk) and dual specificity tyrosine phosphorylation-regulated (Dyrk) kinases: development of chemical probe ML315. Bioorg Med Chem Lett. 2013 Jun15;23(12):3654-61.
3 Tricyclic Pyrimidines As Inhibitors of DYRK1A/DYRK1B As Potential Treatment for Down's Syndrome or Alzheimer's Disease. ACS Med Chem Lett. 2013 Apr 26;4(6):502-3.
4 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2010).