Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTYMGWX)

DTT Name PDK-1 messenger RNA (PDK-1 mRNA) DTT Info
UniProt ID
PDPK1_HUMAN
Gene Name PDPK1

Molecule-Related Drug & Molecule List

Molecule-Related Drug List
Molecule Type:
DTT
DTP
DME
Drug Status:
Investigative Drug(s)
Download the Complete Related Drug List
26 Investigative Drug(s) Transported by This DTP
Drug Name Drug ID Indication ICD 11 Highest Status REF
(Z)-3-((1H-pyrrol-2-yl)methylene)indolin-2-one DM27WDP Discovery agent N.A. Investigative [1]
BX-201 DMGK7U5 Discovery agent N.A. Investigative [1]
BX-517 DMBQIEF Discovery agent N.A. Investigative [1]
ISIS 29219 DM37R5F Discovery agent N.A. Investigative [2]
ISIS 29223 DMMQPFE Discovery agent N.A. Investigative [2]
ISIS 29224 DM9UNWE Discovery agent N.A. Investigative [2]
ISIS 29232 DMLES7J Discovery agent N.A. Investigative [2]
ISIS 29233 DMGV4O7 Discovery agent N.A. Investigative [2]
ISIS 29234 DM1XAPO Discovery agent N.A. Investigative [2]
ISIS 29236 DMAXD7P Discovery agent N.A. Investigative [2]
ISIS 29237 DMPYJEB Discovery agent N.A. Investigative [2]
ISIS 29239 DMHQF1J Discovery agent N.A. Investigative [2]
ISIS 29243 DMZ7UM2 Discovery agent N.A. Investigative [2]
ISIS 29244 DMTHVEL Discovery agent N.A. Investigative [2]
ISIS 29246 DM0DG1K Discovery agent N.A. Investigative [2]
ISIS 29255 DMK2QPU Discovery agent N.A. Investigative [2]
ISIS 29256 DMF1MJ2 Discovery agent N.A. Investigative [2]
ISIS 29257 DMUM2H1 Discovery agent N.A. Investigative [2]
ISIS 29469 DMVCFQ5 Discovery agent N.A. Investigative [2]
ISIS 29470 DMPCK7Y Discovery agent N.A. Investigative [2]
ISIS 29471 DMG4RMZ Discovery agent N.A. Investigative [2]
ISIS 29475 DMEBQUN Discovery agent N.A. Investigative [2]
ISIS 29477 DMKQMXV Discovery agent N.A. Investigative [2]
MiR-375 DM4P9LJ Discovery agent N.A. Investigative [3]
NU-6102 DMMOFKD Discovery agent N.A. Investigative [4]
SU-6689 DMDNA23 Discovery agent N.A. Investigative [1]
------------------------------------------------------------------------------------
⏷ Show the Full List of 26 Investigative Drug(s)
Molecule Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

References

1 Indolinone based phosphoinositide-dependent kinase-1 (PDK1) inhibitors. Part 1: design, synthesis and biological activity. Bioorg Med Chem Lett. 2007 Jul 15;17(14):3814-8.
2 US patent application no. 6,124,272, Antisense modulation of PDK-1 expression.
3 miR-375 targets 3'-phosphoinositide-dependent protein kinase-1 and regulates glucose-induced biological responses in pancreatic beta-cells. Diabetes. 2008 Oct;57(10):2708-17.
4 Triazolo[1,5-a]pyrimidines as novel CDK2 inhibitors: protein structure-guided design and SAR. Bioorg Med Chem Lett. 2006 Mar 1;16(5):1353-7.