Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTZ04AF)

• DTT Name: EGFR T790M mutant (EGFR T790M) DTT Info
• Gene Name: EGFR

Molecule-Related Drug & Molecule List

1 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Osimertinib	DMRJLAT	Non-small-cell lung cancer	2C25.Y	Approved	[1]

1 Patented Agent(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
PMID27774824-Compound-Figure9Example2down	DMXAV42	N. A.	N. A.	Patented	[2]

References

• [1] AZD9291, an irreversible EGFR TKI, overcomes T790M-mediated resistance to EGFR inhibitors in lung cancer. Cancer Discov. 2014 Sep;4(9):1046-61.
• [2] Inhibitors of JAK-family kinases: an update on the patent literature 2013-2015, part 1.Expert Opin Ther Pat. 2017 Feb;27(2):127-143.