Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTZC6DR)

DTT Name	cGMP-dependent protein kinase (cGK) DTT Info
UniProt ID	KGP1_HUMAN; KGP2_HUMAN
Gene Name	PRKG1; PRKG2

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Investigative Drug(s)

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4 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
ARC-1028	DM0KDTG	Discovery agent	N.A.	Investigative	[1]
STAUROSPORINONE	DMU2H4K	Discovery agent	N.A.	Investigative	[2]
TENELLONE A	DM1S209	Discovery agent	N.A.	Investigative	[3]
TENELLONE B	DM9ZVJ7	Discovery agent	N.A.	Investigative	[3]
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Molecule Interaction Atlas

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References

1	Structural analysis of ARC-type inhibitor (ARC-1034) binding to protein kinase A catalytic subunit and rational design of bisubstrate analogue inhi... J Med Chem. 2009 Jan 22;52(2):308-21.
2	Non-glycosidic/non-aminoalkyl-substituted indolocarbazoles as inhibitors of protein kinase C, Bioorg. Med. Chem. Lett. 3(10):1959-1964 (1993).
3	Tenellones A and B from a Diaporthe sp.: two highly substituted benzophenone inhibitors of parasite cGMP-dependent protein kinase activity. J Nat Prod. 2005 Apr;68(4):611-3.