Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTZO9B0)

DTT Name	Interleukin 21 receptor (IL21R) DTT Info
Gene Name	IL21R

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Clinical Trial Drug(s)

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3 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Ab-01	DMOGDCQ	Inflammation	1A00-CA43.1	Phase 2	[1]
AMG 256	DMXYCZV	Solid tumour/cancer	2A00-2F9Z	Phase 1	[2]
ATR-107	DMBCATZ	Crohn disease	DD70	Phase 1	[3]
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Molecule Interaction Atlas

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References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2304).
2	Clinical pipeline report, company report or official report of Amgen.
3	Anti-IL21 receptor monoclonal antibody (ATR-107): Safety, pharmacokinetics, and pharmacodynamic evaluation in healthy volunteers: a phase I, first-in-human study. J Clin Pharmacol. 2014 Jan;54(1):14-22.