Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTT (ID: TTZQTY2)

DTT Name	DMPK messenger RNA (DMPK mRNA) DTT Info
UniProt ID	DMPK_HUMAN
Gene Name	DMPK

Molecule-Related Drug & Molecule List

Molecule-Related Drug List

Molecule Type:

DTT

DTP

DME

Drug Status:

Investigative Drug(s)

Clinical Trial Drug(s)

Download the Complete Related Drug List

1 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
ISIS-DMPK	DMH32LC	Myotonic dystrophy	8C71.0	Phase 1/2	[1]
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3 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
2-MOE phosphorothioate gapmers	DM4IJXW	Myotonic dystrophy	8C71.0	Investigative	[2]
PRO-135	DMA2SBL	Myotonic dystrophy	8C71.0	Investigative	[2]
RKI-1447	DMGTAWC	Discovery agent	N.A.	Investigative	[3]
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Molecule Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

References

1	Clinical pipeline report, company report or official report of ISIS Pharmaceuticals.
2	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1505).
3	Pyridylthiazole-based ureas as inhibitors of Rho associated protein kinases (ROCK1 and 2). Medchemcomm. 2012 Jun 1;3(6):699-709.