Details of Drug-Metabolizing Enzyme (DME)
General Information of Drug-Metabolizing Enzyme (DME) (ID: DE49HWX)
| DME Name | CDP-alcohol phosphatidyltransferase (pgsA) | ||||
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| Synonyms | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; pgsA; AXK38_10040; CYK18_09100; D8842_08295; FBF73_01305; SK1126_1848; SK642_1900 | ||||
| Gene Name | pgsA | ||||
| UniProt ID | |||||
| INTEDE ID | |||||
| EC Number | EC: 2.7.8.5 | ||||
| Lineage | Species: Streptococcus mitis | ||||
| Tissue Distribution | Primarily distributed in human oral cavity. | ||||
| Sequence |
MKKEQIPNLLTIGRILFIPIFIFILTVGNSIESHIVAAIIFAIASITDYLDGYLARKWNV
VSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRELAVTGLRLLLVETGGTVL AAAMPGKIKTFSQMFAIIFLLLHWTLIGQVLLYVALFFTIYSGYDYFKGSAYVFKGTFGS K |
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| Function | This enzyme catalyzes the committed step in the biosynthesis of acidic phospholipids known by the common names phophatidylglycerols and cardiolipins. | ||||
Molecular Interaction Atlas (MIA) of This DME
| Molecular Interaction Atlas (MIA) | ||||||||||||||||||||||||||||
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1 Approved Drug(s) Metabolized by This DME
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