Details of Drug-Metabolizing Enzyme (DME)
General Information of Drug-Metabolizing Enzyme (DME) (ID: DE9THM7)
| DME Name | Sulfatase (sulF) | ||||
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| Synonyms | Dehydroepiandrosterone sulfatase; Sulfate sulfatase; Cholesterol sulfate sulfohydrolase; Arylsufatase; Arylsulfatase C; AtsA; ASC; HMPREF2983_01415 | ||||
| Gene Name | HMPREF2983_01415 | ||||
| UniProt ID | |||||
| INTEDE ID | |||||
| EC Number | EC: 3.1.6.1 | ||||
| Lineage | Species: Prevotella buccae | ||||
| Tissue Distribution | Primarily distributed in human gut. | ||||
| Sequence |
MNMNDKKLIYRNPIYLIGTRFLKLYIIIGLILRIILMHATPGDASFSLGEIVRLLSIGIV
SDFCMAILLALPLLIIYLGLNERKYHRIIGWMIEILLIASFVYVLFFHTIFHEYGGGAPT IARIFLGWKLFSFSMRFFFPKIRETWRRVSLYLTWAVYVFLFLCVTAGEYIFWGEFGVRY NFIAVDYLVYTHEVIGNIMESYAIIPMIGMTLLLTVGIIFLQSRHYRFNITKLYGVKMLI IHLFLYAVLATSAYFILWETHSLKSDNQYVTQLEQNGACDFVIAFQSNKLAYDQFYAMLP KQECISMYRQLSGLNKDGKKNIGDSLAENRPNIVLITVESLSADFLTRYGNKQNLTPRLD RLMQESLVFDSLFAAGNRTVRGLEALSLCLPPSAGESIIKRKANRMGNLSVGSVLSRLGY KSQFIYGGDSYFDNMGDFFSHNGYEVIDRKNIPDNQVTFANIWGVCDEDIFRKSLQVFDT NNKSGHPFFAQIMTTSNHRPYTYPAGKITVNGDPNTREASVKYTDYAIGKFIDDAKKKVW FKNTVFIVIADHCASSAGKTSLPIDRYHIPCLVYAPEIIQQEKIEKICSQIDLMPTVLSL LNLRSSVSFTGQDILAPTYHPRAFMATYQDLGYMEDNRLTVLSPVRNVQQYTLRPLQDGT YDEQLARKTDEKLVRKAQAYYQYTNLYVKAK |
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| Function | This enzyme catalyzes the hydrolysis of sulfate esters. | ||||
Molecular Interaction Atlas (MIA) of This DME
| Molecular Interaction Atlas (MIA) | ||||||||||||||||||||||||||||
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1 Investigative Drug(s) Metabolized by This DME
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