Details of Drug-Metabolizing Enzyme (DME)
General Information of Drug-Metabolizing Enzyme (DME) (ID: DEIRJ6O)
| DME Name | Phospholipase C (plc) | ||||
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| Synonyms | Phosphatidylcholine cholinephosphohydrolase; Gamma-toxin; PLC; plc | ||||
| Gene Name | plc | ||||
| UniProt ID | |||||
| INTEDE ID | |||||
| 3D Structure | |||||
| Gene ID | |||||
| EC Number | EC: 3.1.4.3 | ||||
| Lineage | Species: Clostridium novyi | ||||
| Tissue Distribution | Primarily distributed in human gut. | ||||
| Sequence |
MKKKFLKGLCCAFVISITCLGASSKAYGWDGKKDGTGTHSMIVTQAVKVLENDMSKDEPE
IVKQNFKILQDNMHKFQLGSTYPDYDPNAYKLFQDHFWDPDTDHNFSKDNLWYLSYSIKD TAESQVRKFTALARNEWEKGNYEKATWYFGQAMHYFGDLNTPYHAANVTAVDSIGHTKYE GFAEKRKDQYRINTTGIKTNEGFYADALKNSNFDSWSKEYCKGWAKQAKNLYYSHSTMKH TNEDWDYSASHALKNAQMGTAGCIYRFLYDVSKDLLPTENHKINGLMVVIKTANEIAAGT DDYVYFGIERKDGTVQEWTLDNPGNDFEANQEDTYILKIKKPSIKFSDINRMWIRKANFT PVSDDWKVKGIKVIADGSVQYEKQINKWIHGNEKYYIN |
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| Function | This enzyme is a bacterial zinc protein, and it acts on sphingomyelin and phosphatidylinositol. | ||||
Molecular Interaction Atlas (MIA) of This DME
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2 Investigative Drug(s) Metabolized by This DME
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