Details of Drug-Metabolizing Enzyme (DME)
General Information of Drug-Metabolizing Enzyme (DME) (ID: DEJ4FO2)
| DME Name | Sucrose phosphorylase (Spase) | ||||
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| Synonyms | Sucrose glucosyltransferase; Glucosyltransferase-A; SPase; GTF-A; SP; treY; BBG7_0104; CE169_10215 | ||||
| Gene Name | treY | ||||
| UniProt ID | |||||
| INTEDE ID | |||||
| EC Number | EC: 2.4.1.7 | ||||
| Lineage | Species: Bifidobacterium longum | ||||
| Tissue Distribution | Primarily distributed in human oral cavity. | ||||
| Sequence |
MKNKVQLITYADRLGDGTLSSMTDILRTRFDGVYDGVHILPFFTPFDGADAGFDPIDHTK
VDERLGSWDDVAELSKTHNIMVDAIVNHMSWESKQFQDVLEKGEESEYYPMFLTMSSVFP NGATEEDLAGIYRPRPGLPFTHYNLGGKTRLVWVSFTPQQVDIDTDSAKGWEYLMSIFDQ MAASHVRYIRLDAVGYGAKEAGTSCFMTPKTFKLISRLREEGVKRGLEILIEVHSYYKKQ VEIASKVDRVYDFALPPLLLHSLFTGHVEPVAHWTEIRPNNAVTVLDTHDGIGVIDIGSD QLDRSLKGLVPDEDVDNLVNTIHANTHGESQAATGAAASNLDLYQVNSTYYSALGCNDQH YLAARAVQFFLPGVPQVYYVGALAGRNDMELLRRTNNGRDINRHYYSTAEIDENLERPVV KALNALAKFRNELSAFDGEFSYEVDGDTSITFRWTAADGASTAALTFEPGRGLGTDNATP VASLAWSDAAGDHETHDLLANPPIADID |
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| Function | This enzyme catalyzes the conversion of sucrose to D-fructose and alpha-D-glucose-1-phosphate. | ||||
Molecular Interaction Atlas (MIA) of This DME
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1 Preclinical Drug(s) Metabolized by This DME
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1 Investigative Drug(s) Metabolized by This DME
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