Details of Drug-Metabolizing Enzyme (DME)
General Information of Drug-Metabolizing Enzyme (DME) (ID: DEX542K)
| DME Name | Dipeptidylpeptidase IV (DPP4) | ||||
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| Synonyms |
Bacterial dipeptidyl peptidase 4; Adenosine deaminase binding protein; Adenosine deaminase complexing protein; Adenosine deaminase-binding protein; Amino acyl-prolyl dipeptidyl aminopeptidase; Bacterial DPP4; E8L09_04090
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| Gene Name | DPP4 | ||||
| UniProt ID | |||||
| INTEDE ID | |||||
| EC Number | EC: 3.4.14.5 | ||||
| Lineage | Species: Streptococcus suis | ||||
| Tissue Distribution | Primarily distributed in human blood. | ||||
| Sequence |
MKKTFVRIATFLMLVCLFPVQLVQACSGFIIGKGLTTDGSILYGRTEDYPYPPNNGAHNK
NYIVVPAATYAKGDMLVDESFGFTAPHLANEFKYTSTPDAARGDGSNGNFGAHGFNEKGV SMTATVTAIPNKKILAVDPLVTAGGLGEAILIDYVLPRVTSAREGIELIAKTIDEKGSAE GNIIVIADKNEVWYMEILSGHQYVAIKFPEDKYAIFANTYYLGHVDFTDTENVIASAKVE EVAKQAENYMMVDGKFHIAKSYGPENYADGDRSRTYAGIKLLDPASSVTYEDAVYDLLRQ PTDPSRRFSLQDTFALQRNRFEHLPEFRPDDEAGKVKQGDNGANDQAADATYKYALGNEN VIDAHVYQINSSLPSAFGGTVWLGLAQTRNTPYVPFYGIVTDTYEAFKNRSASYDANSWY WTVQNIDKMAISHPELFGTSIQEKWIALEKEWIAAQAALDAQYAGLSEDAAVALAPTVTE ATLARSAEIFAQLKAVEAEMMAKIEVVTTPSSSGTETSTSTSQSTSTSDTGGATDTSSSS GTVVSSDKKVTPTNKKGKSNLPSTGEQVSILLVALGVAGILTAIFLHRKKSNKE |
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| Function | This enzyme cleaves X-proline or X-alanine dipeptides from the N-terminus of polypeptides. | ||||
Molecular Interaction Atlas (MIA) of This DME
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1 Investigative Drug(s) Metabolized by This DME
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References