Details of Drug Off-Target (DOT)

General Information of Drug Off-Target (DOT) (ID: OTXKFLFB)

DOT Name	Transforming protein v-Fos/v-Fox (FOS-FOX)
Gene Name	FOS-FOX
UniProt ID	FOSX_MSVFR
Pfam ID	PF00170
Sequence	DSLSYYHSPADSFSSMGSPVNTQDFCADLSVSSANFIPTETAISTSPDLQWLVQPTLVSS VAPSQTRAPHPYGLPTQSAGAYARAGMVKTVSGGRAQSIGRRGKVEQLSPEEEVKRRIRR ERNKMAAAKCRNRRRELTDTLQAETDQLEDEKSALQTEIANLLKEKEKLEFILAAHRPAC KIPDDLGFPEEMSVASLDLTGGLLPLLNDPEPKPSLEPVKSSFDDFLFPASSGHSGFISM AGWQ

Molecular Interaction Atlas (MIA) of This DOT

Molecular Interaction Atlas (MIA)

Jump to Detail Molecular Interaction Atlas of This DOT

This DOT Affected the Drug Response of 1 Drug(s)

Drug Name	Drug ID	Highest Status	Interaction	REF
Acetaminophen	DMUIE76	Approved	Transforming protein v-Fos/v-Fox (FOS-FOX) increases the Hepatotoxicity ADR of Acetaminophen.	[1]
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References

1	ADReCS-Target: target profiles for aiding drug safety research and application. Nucleic Acids Res. 2018 Jan 4;46(D1):D911-D917. doi: 10.1093/nar/gkx899.