Details of Drug Off-Target (DOT)
General Information of Drug Off-Target (DOT) (ID: OTYRE3XO)
DOT Name | TP53-target gene 5 protein (TP53TG5) | ||||
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Synonyms | TP53-inducible gene 5 protein | ||||
Gene Name | TP53TG5 | ||||
Related Disease | |||||
UniProt ID | |||||
3D Structure | |||||
Pfam ID | |||||
Sequence |
MSPSAKKRPKNSRVSKMQDEKLRDETEQPVSKVIERNRLRTVLKNLSLLKLLKSSNRRIQ
ELHKLAKRCWHSLLSVPKILRISSGENSACNKTKQNNEEFQEIGCSEKELKSKKLESTGD PKKKEYKEWKSQVQSGMRNKEKTSLAAMPRKEKHIEPEVPRTSRDDSLNPGVQGRQPLTE GPRVIFIKPYRNRTPMGHMKQLDVADQWIWFEGLPTRIHLPAPRVMCRSSTLRWVKRRCT RFCSASLEMPMWHPYKVDVTWTRARGASRGWRSRHQLKGRNGWRNSRVYK |
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Function | May play a significant role in p53/TP53-mediating signaling pathway. | ||||
Tissue Specificity | Highly expressed in heart, brain and small intestine. Less abundant in skeletal muscle, spleen, prostate, ovary and colon. A smaller transcript is expressed specifically in the testis. | ||||
Molecular Interaction Atlas (MIA) of This DOT
1 Disease(s) Related to This DOT
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Molecular Interaction Atlas (MIA) | ||||||||||||||||||||||||||
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1 Drug(s) Affected the Post-Translational Modifications of This DOT
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References