Details of the Drug Combination

General Information of Drug Combination (ID: DC9VYF1)

• Drug Combination Name: PM1183 + PM1183
• Indication: Lymphoid neoplasm; Status: Investigative [1]
• Component Drugs:
  PM1183 (DMZZGWP): N.A.
  PM1183 (DMZZGWP): N.A.
• High-throughput Screening Result:
  Testing Cell Line: Mak
  Zero Interaction Potency (ZIP) Score: 3.186
  Bliss Independence Score: 6.515
  Loewe Additivity Score: 6.507
  LHighest Single Agent (HSA) Score: 3.452

References

• [1] Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.
• [2] Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)