Details of the Drug Combination

General Information of Drug Combination (ID: DCAWFJX)

Drug Combination Name

Bisacodyl Butylscopolamine

Indication

Disease Entry	Status	REF
Constipation - Functional	Phase 1	[1]

Component Drugs

Bisacodyl DM178H9

Butylscopolamine DMZKXB7

Small molecular drug

2D MOL

3D MOL

Molecular Interaction Atlas of This Drug Combination

Molecular Interaction Atlas (MIA)

Indication(s) of Bisacodyl

Disease Entry	ICD 11	Status	REF
Constipation	DD91.1	Approved	[2]

Indication(s) of Butylscopolamine

Disease Entry	ICD 11	Status	REF
Dysmenorrhea	GA34.3	Approved	[2]

Butylscopolamine Interacts with 1 DTT Molecule(s)

DTT Name	DTT ID	UniProt ID	Mode of Action	REF
Muscarinic acetylcholine receptor M5 (CHRM5)	TTH18TF	ACM5_HUMAN	Modulator	[3]
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References

1	ClinicalTrials.gov (NCT03226145) Reclassifying Constipation Using Imaging and Manometry
2	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
3	Comparison of pharmacological effects of L- and DL-n-butyl-scopolamine in rat uterus. Yao Xue Xue Bao. 1994;29(1):24-7.