Details of the Drug Combination

General Information of Drug Combination (ID: DCCT9AW)

Drug Combination Name
Prilocaine Prilocaine
Indication
Disease Entry Status REF
Other Surgical Procedures Phase 1 [1]
Component Drugs Prilocaine   DMI7DZ2 Prilocaine   DMI7DZ2
Small molecular drug Small molecular drug
2D MOL 2D MOL
3D MOL 3D MOL

Molecular Interaction Atlas of This Drug Combination

Molecular Interaction Atlas (MIA)
Indication(s) of Prilocaine
Disease Entry ICD 11 Status REF
Pain MG30-MG3Z Approved [2]
Premature ejaculation HA03.0Z Investigative [3]
Prilocaine Interacts with 1 DTT Molecule(s)
DTT Name DTT ID UniProt ID Mode of Action REF
Voltage-gated sodium channel alpha Nav1.5 (SCN5A) TTZOVE0 SCN5A_HUMAN Blocker [4]
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Indication(s) of Prilocaine
Disease Entry ICD 11 Status REF
Pain MG30-MG3Z Approved [2]
Premature ejaculation HA03.0Z Investigative [3]
Prilocaine Interacts with 1 DTT Molecule(s)
DTT Name DTT ID UniProt ID Mode of Action REF
Voltage-gated sodium channel alpha Nav1.5 (SCN5A) TTZOVE0 SCN5A_HUMAN Blocker [4]
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References

1 ClinicalTrials.gov (NCT01643616) Ultrasound Guided Distal Sciatic Nerve Block - a Comparison With Nerve Stimulator Technique
2 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7276).
3 Prilocaine FDA Label
4 Monoamine transporter and sodium channel mechanisms in the rapid pressor response to cocaine. Pharmacol Biochem Behav. 1998 Feb;59(2):305-12.