Details of the Drug Combination

General Information of Drug Combination (ID: DCO3VDY)

Drug Combination Name

Vericiguat Vericiguat

Indication

Disease Entry	Status	REF
Heart Failure	Phase 1	[1]

Component Drugs

Vericiguat DM7MDBE

Small molecular drug

2D MOL

3D MOL

Molecular Interaction Atlas of This Drug Combination

Molecular Interaction Atlas (MIA)

Indication(s) of Vericiguat

Disease Entry	ICD 11	Status	REF
Heart failure	BD10-BD13	Approved	[2]

Vericiguat Interacts with 1 DTT Molecule(s)

DTT Name	DTT ID	UniProt ID	Mode of Action	REF
Soluble guanylyl cyclase (GUCY2D)	TTWNFC2	GUC2D_HUMAN	Modulator	[2]
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Indication(s) of Vericiguat

Disease Entry	ICD 11	Status	REF
Heart failure	BD10-BD13	Approved	[2]

Vericiguat Interacts with 1 DTT Molecule(s)

DTT Name	DTT ID	UniProt ID	Mode of Action	REF
Soluble guanylyl cyclase (GUCY2D)	TTWNFC2	GUC2D_HUMAN	Modulator	[2]
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References

1	ClinicalTrials.gov (NCT05086952) A Study in Healthy Adult Male Participants to Learn the Way Vericiguat is Absorbed With and Without Food When Taken as a Single Dose in Liquid Form Suitable for Children Compared to a 10 Milligram (mg) Tablet That Releases the Active Substance Immediately
2	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health Human Services. 2021