Details of the Drug Combination

General Information of Drug Combination (ID: DCZDNXX)

Drug Combination Name

Piperacetazine PM1183

Indication

Disease Entry	Status	REF
Lymphoid neoplasm	Investigative	[1]

Component Drugs

Piperacetazine DMGQU0Y

PM1183 DMZZGWP

Small molecular drug

N.A.

High-throughput Screening Result

Testing Cell Line: Mak

Zero Interaction Potency (ZIP) Score: 6.406

Bliss Independence Score: 10.963

Loewe Additivity Score: 3.661

LHighest Single Agent (HSA) Score: 3.035

Molecular Interaction Atlas of This Drug Combination

Molecular Interaction Atlas (MIA)

Indication(s) of Piperacetazine

Disease Entry	ICD 11	Status	REF
Schizophrenia	6A20	Approved	[2]

Piperacetazine Interacts with 1 DTT Molecule(s)

DTT Name	DTT ID	UniProt ID	Mode of Action	REF
Dopamine D2 receptor (D2R)	TTEX248	DRD2_HUMAN	Modulator	[4]
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Indication(s) of PM1183

Disease Entry	ICD 11	Status	REF
Ovarian cancer	2C73	Phase 3	[3]

References

1	CheMBL Affinity Phenotypic Cellular Interaction Assay ID: CHEMBL1125966
2	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
3	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
4	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.