Details of the Drug Combinations

General Information of This Drug (ID: DM0RKS4)

Drug Name
Bepridil   DM0RKS4
Synonyms
Bepadin; Vascor; CERM 1978; Bepadin (TN); Bepridil (INN); Vascor (TN); N-benzyl-N-[3-(2-methylpropoxy)-2-pyrrolidin-1-ylpropyl]aniline; Beta-((2-Methylpropoxy)methyl)-N-phenyl-N-(phenylmethyl)-1-pyrrolidineethanamine; N-Benzyl-N-[3-(2-methylpropoxy)-2-pyrrolidin-1-yl-propyl]aniline hydrochloride; N-benzyl-N-[3-(2-methylpropoxy)-2-(pyrrolidin-1-yl)propyl]aniline; N-{3-[(2-methylpropyl)oxy]-2-pyrrolidin-1-ylpropyl}-N-(phenylmethyl)aniline
Indication
Disease Entry ICD 11 Status REF
Chronic/stable angina BA40.1 Approved [1]
Therapeutic Class
Antiarrhythmic Agents
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

74 Investigative Drug Combination(s) Consisting of This drug
Normalized Drug Combination Synergy Score
Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.
DrugCom Name DrugCom ID Component Drug Indication REF
Allopurinol + Bepridil DCGK0JK Allopurinol Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Aminosalicylic acid + Bepridil DCCI6MR Aminosalicylic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Arfolitixorin + Bepridil DCKYWT5 Arfolitixorin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Artemisinin + Bepridil DC0MET7 Artemisinin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Asenapine + Bepridil DCSJBLB Asenapine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Azatadine + Bepridil DCY5S65 Azatadine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Bepridil + PMID28460551-Compound-2 DCJEX0L PMID28460551-Compound-2 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Bepridil + Vinblastine DCYJ912 Vinblastine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Bepridil + Mephenytoin DCK6Y7F Mephenytoin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Bepridil + Isosorbide dinitrate DC69LEJ Isosorbide dinitrate Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Bepridil + Metyrosine DCAPM5K Metyrosine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Bepridil + Efavirenz DCC5CGX Efavirenz Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Bepridil + Amodiaquine DCLQXHP Amodiaquine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Bepridil + Chlorzoxazone DC8MG7H Chlorzoxazone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Bepridil + Marizomib DCX8MJ1 Marizomib Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [2]
Bepridil + Galantamine DC5BTZS Galantamine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Bepridil + Ciprofibrate DCTNQIP Ciprofibrate Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Bepridil + Nizatidine DC7D3AQ Nizatidine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Bepridil + Dichlorphenamide DC6Z5SC Dichlorphenamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Bepridil + Clopidogrel DCHBHQO Clopidogrel Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Bepridil + Triflupromazine DC7NOK4 Triflupromazine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Bepridil + BIO-300 DCIFTV0 BIO-300 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Bepridil + PF-02545920 DCPBSW7 PF-02545920 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Bepridil + Lubiprostone DC0SVKA Lubiprostone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Bepridil + Tiagabine DCWWZZE Tiagabine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Bepridil + GINKGOLIDE A DC7CQDZ GINKGOLIDE A Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Bepridil + Diazoxide DCKTIVH Diazoxide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Bepridil + Fenoprofen DCSTD3B Fenoprofen Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Bepridil + Idarubicin DCKENL9 Idarubicin Glioblastoma? (Cell Line: T98G) [2]
Bepridil + Maprotiline DCAYVHA Maprotiline Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Bepridil + Ethambutol DCFZARX Ethambutol Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Bepridil + Leflunomide DCSGNNL Leflunomide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Bepridil + Hyodeoxycholic acid DC3E4PN Hyodeoxycholic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Bepridil + Iloprost DCFH738 Iloprost Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Bepridil + Testolactone DCRFTRU Testolactone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Bepridil + Auranofin DCINEYX Auranofin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Bepridil + Cerivastatin DCSHOOQ Cerivastatin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Bepridil + ML323 DC07MEV ML323 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Bepridil + Raltegravir DCVO4QR Raltegravir Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Bepridil + Cytarabine DCZW86T Cytarabine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Bortezomib + Bepridil DC0VEIK Bortezomib Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Bosentan + Bepridil DC8Y0LF Bosentan Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Brincidofovir + Bepridil DCK9UVU Brincidofovir Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Chloroquine + Bepridil DCFDZER Chloroquine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Clascoterone + Bepridil DCE4CS8 Clascoterone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + Bepridil DCR7GZL Dantrolene Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diethylcarbamazine + Bepridil DC4OEBI Diethylcarbamazine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Doxorubicin + Bepridil DCITJ2L Doxorubicin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Endoxifen + Bepridil DCJWIS3 Endoxifen Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Entacapone + Bepridil DCHJW20 Entacapone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Epinephrine + Bepridil DCLUIYX Epinephrine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Everolimus + Bepridil DCGSKCQ Everolimus Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Flavonoid derivative 1 + Bepridil DCXU1TQ Flavonoid derivative 1 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
FORMESTANE + Bepridil DC5PVYP FORMESTANE Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Ginsenoside Rb1 + Bepridil DC8WAVN Ginsenoside Rb1 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
GSK2194069 + Bepridil DCMNH0Q GSK2194069 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Guanfacine + Bepridil DCESPP2 Guanfacine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Imatinib + Bepridil DCQIBBF Imatinib Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Itraconazole + Bepridil DCIRWKS Itraconazole Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Kanamycin + Bepridil DCP6VTZ Kanamycin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Mecamylamine + Bepridil DCZRL8T Mecamylamine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Mycophenolic acid + Bepridil DCXLTRJ Mycophenolic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Pazopanib + Bepridil DCDQJGP Pazopanib Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Pentamidine + Bepridil DCKF00L Pentamidine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Pentostatin + Bepridil DCP6QC7 Pentostatin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Pomalidomide + Bepridil DCSSOK3 Pomalidomide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Quinine + Bepridil DC0FHGU Quinine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Sitagliptin + Bepridil DCDOG1G Sitagliptin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Tamoxifen + Bepridil DCJLH7N Tamoxifen Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Terameprocol + Bepridil DCOZ00Z Terameprocol Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Testosterone + Bepridil DCS5LWP Testosterone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Trimethobenzamide + Bepridil DCIF01W Trimethobenzamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Vorinostat + Bepridil DC81YEJ Vorinostat Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Zileuton + Bepridil DCDPLWY Zileuton Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
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⏷ Show the Full List of 74 DrugCom(s)

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2337).
2 Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.