Details of the Drug Combinations

General Information of This Drug (ID: DM1D8XY)

Drug Name
Dantrolene   DM1D8XY
Synonyms
Dantrium; Dantroleno; Dantrolenum; DANTROLENE SODIUM; Dantrium Intravenous; Dantrium (TN); Dantrolen (TN); Dantroleno [INN-Spanish]; Dantrolenum [INN-Latin]; F-368; Dantrolene (USAN/INN); Dantrolene [USAN:BAN:INN]; 1-(((5-(4-Nitrophenyl)-2-furanyl)methylene)amino)-2,4-imidazolidinedione; 1-((5-(p-Nitrophenyl)furfurylidene)amino)hydantoin; 1-({(1E)-[5-(4-nitrophenyl)furan-2-yl]methylidene}amino)imidazolidine-2,4-dione; 1-({[5-(4-nitrophenyl)furan-2-yl]methylidene}amino)imidazolidine-2,4-dione; 1-[(E)-[5-(4-nitrophenyl)furan-2-yl]methylideneamino]imidazolidine-2,4-dione
Indication
Disease Entry ICD 11 Status REF
Hyperthermia MG26 Approved [1]
Therapeutic Class
Muscle Relaxants
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

158 Investigative Drug Combination(s) Consisting of This drug
Normalized Drug Combination Synergy Score
Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.
DrugCom Name DrugCom ID Component Drug Indication REF
Abacavir + Dantrolene DCZ3BX6 Abacavir Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acamprosate + Dantrolene DCNY6S3 Acamprosate Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acetazolamide + Dantrolene DCON6T7 Acetazolamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acetohydroxamic Acid + Dantrolene DCSJSMQ Acetohydroxamic Acid Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Aciclovir + Dantrolene DCV62LL Aciclovir Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Aliskiren + Dantrolene DCXQNB4 Aliskiren Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Anamorelin + Dantrolene DC12GVL Anamorelin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Armodafinil + Dantrolene DCCTYY6 Armodafinil Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Artemisinin + Dantrolene DC5X981 Artemisinin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Atovaquone + Dantrolene DC47KDZ Atovaquone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
BIO-300 + Dantrolene DC89H1M BIO-300 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Bumetanide + Dantrolene DC7QHMT Bumetanide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Busulfan + Dantrolene DCAHW6K Busulfan Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Chlorambucil + Dantrolene DCQPY7I Chlorambucil Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Chlormezanone + Dantrolene DCSHI1U Chlormezanone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Chlorzoxazone + Dantrolene DC5LKB4 Chlorzoxazone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cilastatin + Dantrolene DCY85OW Cilastatin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cilostazol + Dantrolene DCBVLZL Cilostazol Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cisatracurium + Dantrolene DCLOB77 Cisatracurium Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Crotamiton + Dantrolene DCKCI9J Crotamiton Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cycloguanil + Dantrolene DCZMLNZ Cycloguanil Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cytarabine + Dantrolene DC6MXGU Cytarabine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + Ribavirin-TP DCC56M7 Ribavirin-TP Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + Mebutamate DCWOH46 Mebutamate Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + Picoplatin DC7B039 Picoplatin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + Bepridil DCR7GZL Bepridil Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + Primidone DC05UEB Primidone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + Paromomycin DC60IV0 Paromomycin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + Diethylcarbamazine DCARSK9 Diethylcarbamazine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + Citalopram DCOKUY2 Citalopram Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + Triamterene DCPHGIH Triamterene Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + Dactinomycin DCRAI32 Dactinomycin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + Terazosin DCQ5D4J Terazosin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + Tindamax DC1GCE5 Tindamax Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + Furazolidone DCL3BQ4 Furazolidone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + LIAROZOLE DCBOHYQ LIAROZOLE Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + Tacrine DCWF005 Tacrine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + Vinblastine DCWGYS8 Vinblastine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + Fomepizole DCHJP2F Fomepizole Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + Dexmedetomidine DC8S14Z Dexmedetomidine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + Tranexamic acid DCPAEUK Tranexamic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + Dronedarone DCFX2FV Dronedarone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + IT-141 DCL6NYB IT-141 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + Methylergonovine DCV9UMZ Methylergonovine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + Metyrosine DCJCZF1 Metyrosine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + Efavirenz DCI7RWC Efavirenz Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + SCH 727965 DCBZP5I SCH 727965 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + Flavonoid derivative 1 DCBSPCR Flavonoid derivative 1 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + Emetine DCG9LQO Emetine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + Carglumic acid DCR7P02 Carglumic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + Metformin DCE99AQ Metformin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + Aminosalicylic acid DC5TVRW Aminosalicylic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + Galantamine DCX6MRW Galantamine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + Ginsenoside Rb1 DC66QHQ Ginsenoside Rb1 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + GS4071 DC8IX1Z GS4071 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + WAY-100635 DCPJEQ1 WAY-100635 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + Sitagliptin DC5UONS Sitagliptin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + Nizatidine DCY1IYV Nizatidine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + Naringenin DCNYV5L Naringenin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + Clopidogrel DCA251E Clopidogrel Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + Tolazoline DC864Y0 Tolazoline Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + Tolvaptan DCB6KGF Tolvaptan Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + Arfolitixorin DCCHYUL Arfolitixorin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + Eflornithine DC3NK95 Eflornithine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + PF-02545920 DCOMZ0Q PF-02545920 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + Norcisapride DC4GGA2 Norcisapride Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + Lubiprostone DCY4HGS Lubiprostone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + Trifluoperazine DC8DP88 Trifluoperazine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + Oseltamivir DCKH35H Oseltamivir Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + Allopurinol DC6ROCR Allopurinol Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + Benserazide DCK0MD7 Benserazide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + Pargyline DCP1AO3 Pargyline Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + Idarubicin DC7ND7W Idarubicin Glioblastoma? (Cell Line: T98G) [2]
Dantrolene + Methocarbamol DCEEN32 Methocarbamol Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + Probenecid DC0B9A1 Probenecid Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + Acamprosate DC03ZGB Acamprosate Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + Moricizine DCTTEWN Moricizine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + Topotecan DCBNIBQ Topotecan Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + Clascoterone DCEV30Q Clascoterone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + Cefmenoxime DC2L6VX Cefmenoxime Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + Maprotiline DC8QQE4 Maprotiline Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + Ethambutol DCU6HM5 Ethambutol Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + Acarbose DCZLZ1Z Acarbose Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + Amiloride DCTOTEK Amiloride Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + Brincidofovir DCJJL4E Brincidofovir Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + Asenapine DCHIKQ9 Asenapine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + Maraviroc DCDJGTI Maraviroc Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + Dextromethorphan DCD82PM Dextromethorphan Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + Lacosamide DC2L73L Lacosamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + Doxorubicin DCSLN3G Doxorubicin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + Nitisinone DCVLCPK Nitisinone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + Sumatriptan DCRHS3J Sumatriptan Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + Rufinamide DCZKCY8 Rufinamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + PMID28870136-Compound-43 DCQ9UWH PMID28870136-Compound-43 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + Vorinostat DCXO1IV Vorinostat Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + Cerivastatin DC002EJ Cerivastatin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + AS-1949490 DCBW8IR AS-1949490 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + GSK2194069 DCCMKGS GSK2194069 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Dantrolene + Azatadine DCMXY3B Azatadine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Darunavir + Dantrolene DCLJKFG Darunavir Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Enalaprilat + Dantrolene DCZ1GEY Enalaprilat Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Entacapone + Dantrolene DC7A200 Entacapone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Eptifibatide + Dantrolene DCV564T Eptifibatide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Ethinyl estradiol + Dantrolene DC1P2H0 Ethinyl estradiol Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Ezetimibe + Dantrolene DCU5A9W Ezetimibe Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Fenoprofen + Dantrolene DCADY72 Fenoprofen Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Fibrates + Dantrolene DCVDKWQ Fibrates Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Fluspirilene + Dantrolene DCOH2N5 Fluspirilene Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
FORMESTANE + Dantrolene DCQ3WYL FORMESTANE Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Fosfomycin + Dantrolene DCCQ2HR Fosfomycin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Guanfacine + Dantrolene DC5DKMD Guanfacine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
GYKI-52466 + Dantrolene DCWVJSA GYKI-52466 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Hydralazine + Dantrolene DCF7027 Hydralazine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Hydroxychloroquine + Dantrolene DC1IQIG Hydroxychloroquine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Ibutilide + Dantrolene DCQIJ9G Ibutilide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Idarubicin + Dantrolene DC2C2QK Idarubicin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Iloprost + Dantrolene DCF37KK Iloprost Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Itraconazole + Dantrolene DCPXO03 Itraconazole Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
L-165041 + Dantrolene DCZ8TJK L-165041 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Lefaxin + Dantrolene DCYTQ8C Lefaxin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Linagliptin + Dantrolene DC15KQX Linagliptin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Lithium Citrate + Dantrolene DCTF7UD Lithium Citrate Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Lumefantrine + Dantrolene DC1IGYR Lumefantrine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Memantine + Dantrolene DCEQS9F Memantine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Mephenytoin + Dantrolene DCSMQ7F Mephenytoin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Mesalazine + Dantrolene DCFSQDL Mesalazine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Methylene blue + Dantrolene DCEUFA5 Methylene blue Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Miconazole + Dantrolene DCA8ICG Miconazole Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Mycophenolic acid + Dantrolene DCI70YI Mycophenolic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Nabilone + Dantrolene DCSCWO4 Nabilone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Naltrexone + Dantrolene DC86N4P Naltrexone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Nitrosoglutathione + Dantrolene DCQ0DCW Nitrosoglutathione Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Olmesartan medoxomil + Dantrolene DC5U5WO Olmesartan medoxomil Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Oxandrolone + Dantrolene DC0GY35 Oxandrolone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Oxyphenbutazone + Dantrolene DCIWXVC Oxyphenbutazone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Pentostatin + Dantrolene DC7UV5U Pentostatin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
PHA-739358 + Dantrolene DCIF1VV PHA-739358 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Phensuximide + Dantrolene DCCF7PH Phensuximide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Pomalidomide + Dantrolene DCUVCI8 Pomalidomide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Pramipexole + Dantrolene DCQJHWT Pramipexole Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Pyrazinamide + Dantrolene DC4P3HO Pyrazinamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Raltegravir + Dantrolene DCVS3N7 Raltegravir Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Silver sulfadiazine + Dantrolene DCZEI59 Silver sulfadiazine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Sivelestat + Dantrolene DC0CRME Sivelestat Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Sorafenib + Dantrolene DCAQKW5 Sorafenib Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Spironolactone + Dantrolene DCXTWHT Spironolactone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Sulfapyridine + Dantrolene DCXIFZM Sulfapyridine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Sulfinpyrazone + Dantrolene DC6TSF5 Sulfinpyrazone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Tacrolimus + Dantrolene DCM1U40 Tacrolimus Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Tamoxifen + Dantrolene DCV27XQ Tamoxifen Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Testolactone + Dantrolene DC1DIMB Testolactone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Testosterone cypionate + Dantrolene DCZTZFG Testosterone cypionate Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Trihexyphenidyl + Dantrolene DCVGBGL Trihexyphenidyl Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Triiodothyronine + Dantrolene DC7RFWB Triiodothyronine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Trimethobenzamide + Dantrolene DCWSFH6 Trimethobenzamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Tropisetron + Dantrolene DCKPXU2 Tropisetron Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Valproic Acid + Dantrolene DCCUNNB Valproic Acid Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Zileuton + Dantrolene DCMT52L Zileuton Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
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⏷ Show the Full List of 158 DrugCom(s)

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4172).
2 Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.