Details of the Drug Combinations

General Information of This Drug (ID: DM1TSHL)

Drug Name

Taprenepag DM1TSHL

Synonyms

Taprenepag isopropyl; CP-544326; PF-04217329; PF-4217329

Indication

Disease Entry	ICD 11	Status	REF
Glaucoma/ocular hypertension	9C61	Phase 2	[1]
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Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

2 Clinical Trial Drug Combination(s) Consisting of This drug

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Taprenepag + Latanoprost	DCA1TWQ	Latanoprost	Glaucoma, Open-Angle	[2]
Taprenepag + Latanoprost	DCA57J9	Latanoprost	Primary Open-Angle Glaucoma	[3]
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References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5816).
2	ClinicalTrials.gov (NCT00934089) A Phase 2 Study Of The 24-Hour Intraocular Pressure Lowering And Systemic Exposure Of PF-04217329
3	ClinicalTrials.gov (NCT00572455) Safety and Efficacy of PF-04217329 in Patients With Glaucoma or Elevated Eye Pressure.