Details of the Drug Combinations

General Information of This Drug (ID: DM1XT4N)

Drug Name

Tafenoquine DM1XT4N

Synonyms

106635-80-7; WR-238605; WR 238605; Etaquine; WR238605; Tafenoquine [INN:BAN

Indication

Disease Entry	ICD 11	Status	REF
Malaria	1F40-1F45	Approved	[1]
Plasmodium vivax malaria	1F41	Approved	[1]
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Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

4 Clinical Trial Drug Combination(s) Consisting of This drug

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Tafenoquine + Chloroquine	DC597WV	Chloroquine	Malaria	[2]
Tafenoquine + Chloroquine	DCH4DDM	Chloroquine	Malaria, Vivax	[3]
Tafenoquine + Chloroquine	DCUK86Y	Chloroquine	Malaria, Vivax	[4]
Tafenoquine + Artemether	DC12ZVN	Artemether	Plasmodium Vivax Malaria	[5]
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References

1	Tafenoquine: First Global Approval.Drugs. 2018 Sep;78(14):1517-1523.
2	ClinicalTrials.gov (NCT01205178) G6PD (Glucose-6-phosphate Dehydrogenase) Study to Evaluate Hemolysis Potential of TFQ (Tafenoquine)
3	ClinicalTrials.gov (NCT01376167) Ph 2B/3 Tafenoquine (TFQ) Study in Prevention of Vivax Relapse
4	ClinicalTrials.gov (NCT02563496) A Pharmacokinetics, Safety and Efficacy Study of Tafenoquine (TQ) in Pediatric Subjects With Plasmodium Vivax (P. Vivax) Malaria
5	ClinicalTrials.gov (NCT04704999) Southeast Asia Dose Optimization of Tafenoquine