Details of the Drug Combinations

General Information of This Drug (ID: DM2SZ3F)

Drug Name

SB-612111 DM2SZ3F

Synonyms

N/OFQ receptor antagonist (inflammatory disease), SRI International

Indication

Disease Entry	ICD 11	Status	REF
Inflammation	1A00-CA43.1	Investigative	[1]
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Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

2 Investigative Drug Combination(s) Consisting of This drug

Normalized Drug Combination Synergy Score

Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
MK-4815 + SB-612111	DCS4T2R	MK-4815	Hepatoblastoma (Cell Line: HB3)	[2]
Suramin + SB-612111	DC4M05T	Suramin	DD2 (Cell Line: DD2)	[3]
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References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1693).
2	CheMBL Affinity Phenotypic Cellular Interaction Assay ID: CHEMBL1125976
3	CheMBL Affinity Phenotypic Cellular Interaction Assay ID: CHEMBL1125966