Details of the Drug Combinations

General Information of This Drug (ID: DM5GFIK)

Drug Name

Icotinib hydrochloride DM5GFIK

Synonyms

Conmana; Conmanna; Icotinib; BPI-2009-H

Indication

Disease Entry	ICD 11	Status	REF
Non-small-cell lung cancer	2C25.Y	Registered	[1]
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Drug Type

Small molecular drug

Structure

3D MOL is unavailable

2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

3 Clinical Trial Drug Combination(s) Consisting of This drug

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Icotinib hydrochloride + Gemcitabine	DCE84A5	Gemcitabine	Pancreatic Cancer	[2]
Al3818 + Icotinib hydrochloride	DCB0F43	Al3818	Non Small Cell Lung Cancer	[3]
Gefitinib + Icotinib hydrochloride	DC6LBVW	Gefitinib	Non-Small-Cell Lung Cancer	[4]
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References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7641).
2	ClinicalTrials.gov (NCT02278458) Combination of Icotinib and Gemcitabine as First-line Treatment in Pancreatic Cancer
3	ClinicalTrials.gov (NCT04797806) Study of Anlotinib Combined With Icotinib as the First-line Treatment in Patients With EGFR Concomitant Mutation NSCLC
4	ClinicalTrials.gov (NCT02031601) Intercalated Combination of Chemotherapy and Tyrosine Kinase Inhibitors as First-line Treatment for Patients With Non-Small-Cell Lung Cancer