Details of the Drug Combinations

General Information of This Drug (ID: DM6U9CQ)

Drug Name
Pazopanib HCl   DM6U9CQ
Synonyms Votrient (TN)
Indication
Disease Entry ICD 11 Status REF
Renal cell carcinoma 2C90 Approved [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

47 Investigative Drug Combination(s) Consisting of This drug
Normalized Drug Combination Synergy Score
Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.
DrugCom Name DrugCom ID Component Drug Indication REF
Acamprosate + Pazopanib HCl DCCKFQO Acamprosate Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Aciclovir + Pazopanib HCl DCMZ18O Aciclovir Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Bortezomib + Pazopanib HCl DC7ZNF3 Bortezomib Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Brincidofovir + Pazopanib HCl DC4BMK5 Brincidofovir Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diphenidol + Pazopanib HCl DCT6ETP Diphenidol Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Epinephrine + Pazopanib HCl DCFF0J7 Epinephrine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Ethinyl estradiol + Pazopanib HCl DCPKS22 Ethinyl estradiol Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Imatinib + Pazopanib HCl DC4G760 Imatinib Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
JZL195 + Pazopanib HCl DCYZ6UN JZL195 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Levamisole + Pazopanib HCl DCJXY2X Levamisole Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Loperamide + Pazopanib HCl DC8G9A9 Loperamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Maprotiline + Pazopanib HCl DC3YDKZ Maprotiline Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Mycophenolic acid + Pazopanib HCl DCNWEFO Mycophenolic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Niclosamide + Pazopanib HCl DCBYVFT Niclosamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Novobiocin + Pazopanib HCl DCL38JR Novobiocin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Oxyphenbutazone + Pazopanib HCl DC2VN2O Oxyphenbutazone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Pazopanib + Pazopanib HCl DC2IFKJ Pazopanib Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Pazopanib HCl + Triiodothyronine DC48O2F Triiodothyronine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Pazopanib HCl + Imipramine DCUI5UB Imipramine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Pazopanib HCl + Crotamiton DCSZZVZ Crotamiton Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Pazopanib HCl + Everolimus DCIT9CE Everolimus Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Pazopanib HCl + IT-141 DCZD6W7 IT-141 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Pazopanib HCl + Chlorzoxazone DCA5DU7 Chlorzoxazone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Pazopanib HCl + Docetaxel DC0933B Docetaxel Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Pazopanib HCl + Phenprocoumon DC38S1L Phenprocoumon Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Pazopanib HCl + Aminosalicylic acid DCL7OFC Aminosalicylic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Pazopanib HCl + Eflornithine DCG1G5N Eflornithine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Pazopanib HCl + Diazoxide DC2ALAO Diazoxide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Pazopanib HCl + Darunavir DC43DKJ Darunavir Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Pazopanib HCl + Methylene blue DCMP6U2 Methylene blue Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Pazopanib HCl + Enalaprilat DC2Z9ZH Enalaprilat Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Pazopanib HCl + Maprotiline DCJG41A Maprotiline Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Pazopanib HCl + Teriflunomide DC37WFG Teriflunomide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Pazopanib HCl + Chlorambucil DCPIGJ2 Chlorambucil Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Pazopanib HCl + Endoxifen DCRTD2D Endoxifen Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Pazopanib HCl + Vorinostat DC50Y6L Vorinostat Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Pazopanib HCl + Cerivastatin DCAKMW0 Cerivastatin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Pazopanib HCl + Busulfan DCYNRSG Busulfan Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Pazopanib HCl + Raltegravir DC24OPM Raltegravir Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Pentamidine + Pazopanib HCl DCRTRW8 Pentamidine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Pizotyline + Pazopanib HCl DC9JJFC Pizotyline Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Probenecid + Pazopanib HCl DCLVKQO Probenecid Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Testosterone cypionate + Pazopanib HCl DC7SM5B Testosterone cypionate Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Tiagabine + Pazopanib HCl DCLSLRO Tiagabine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Triapine + Pazopanib HCl DC3VPRX Triapine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triflupromazine + Pazopanib HCl DCVOKHK Triflupromazine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Ursodeoxycholic acid + Pazopanib HCl DCFC229 Ursodeoxycholic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
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⏷ Show the Full List of 47 DrugCom(s)

References

1 Hughes B: 2009 FDA drug approvals. Nat Rev Drug Discov. 2010 Feb;9(2):89-92.
2 Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.
3 Loss of function mutations in VARS encoding cytoplasmic valyl-tRNA synthetase cause microcephaly, seizures, and progressive cerebral atrophy.Hum Genet. 2018 Apr;137(4):293-303. doi: 10.1007/s00439-018-1882-3. Epub 2018 Apr 24.