Details of the Drug Combinations

General Information of This Drug (ID: DM9X2IF)

Drug Name

Verdinexor DM9X2IF

Synonyms

Verdinexor; Verdinexor (KPT-335); KPT-335; UNII-85Q03215IW; Verdinexor; VerdinexorKPT-335; Verdinexor (USAN/INN); EX-A871; KPT 335

Indication

Disease Entry	ICD 11	Status	REF
Coronavirus Disease 2019 (COVID-19)	1D6Y	Investigative	[1]
------------------------------------------------------------------------------------

Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

2 Investigative Drug Combination(s) Consisting of This drug

Normalized Drug Combination Synergy Score

Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Verdinexor + Panobinostat	DCYP0JG	Panobinostat	Diffuse intrinsic pontine glioma (Cell Line: DIPG25)	[2]
Verdinexor + Marizomib	DC1585R	Marizomib	Diffuse intrinsic pontine glioma (Cell Line: DIPG25)	[2]
------------------------------------------------------------------------------------

References

1	A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing. March 27, 2020.
2	Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.