Details of the Drug Combinations

General Information of This Drug (ID: DMB0NVQ)

Drug Name
Steroid derivative 1   DMB0NVQ
Synonyms PMID26882240-Compound-23
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

15 Investigative Drug Combination(s) Consisting of This drug
Normalized Drug Combination Synergy Score
Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.
DrugCom Name DrugCom ID Component Drug Indication REF
ABT-263 + Steroid derivative 1 DCYLZPV ABT-263 Ewing sarcoma (Cell Line: TC-71) [1]
AXL-1717 + Steroid derivative 1 DCL1B7G AXL-1717 Ewing sarcoma (Cell Line: TC-71) [2]
Efaproxyn + Steroid derivative 1 DC146N0 Efaproxyn Ewing sarcoma (Cell Line: TC-71) [2]
Methotrexate + Steroid derivative 1 DC3Y75U Methotrexate Ewing sarcoma (Cell Line: TC-71) [2]
Miconazole + Steroid derivative 1 DCZM50T Miconazole Hepatoblastoma (Cell Line: HB3) [1]
MK-2206 + Steroid derivative 1 DCFK3CS MK-2206 Ewing sarcoma (Cell Line: TC-71) [2]
Nintedanib + Steroid derivative 1 DC0ZE8H Nintedanib Ewing sarcoma (Cell Line: TC-71) [2]
Steroid derivative 1 + Buparlisib DC4OTD0 Buparlisib Ewing sarcoma (Cell Line: TC-71) [2]
Steroid derivative 1 + AZD8055 DC1G572 AZD8055 Ewing sarcoma (Cell Line: TC-71) [2]
Steroid derivative 1 + Everolimus DCGA8W4 Everolimus Ewing sarcoma (Cell Line: TC-71) [2]
Steroid derivative 1 + SCH 727965 DCGM5BR SCH 727965 Ewing sarcoma (Cell Line: TC-71) [2]
Steroid derivative 1 + THAPSIGARGIN DCK6OL7 THAPSIGARGIN Ewing sarcoma (Cell Line: TC-71) [2]
Steroid derivative 1 + OSI-906 DC9ITHJ OSI-906 Ewing sarcoma (Cell Line: TC-71) [2]
Steroid derivative 1 + Bardoxolone methyl DCW1MDW Bardoxolone methyl Ewing sarcoma (Cell Line: TC-71) [2]
Steroid derivative 1 + Romidepsin DC9O74K Romidepsin Ewing sarcoma (Cell Line: TC-71) [2]
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⏷ Show the Full List of 15 DrugCom(s)

References

1 Loss of function mutations in VARS encoding cytoplasmic valyl-tRNA synthetase cause microcephaly, seizures, and progressive cerebral atrophy.Hum Genet. 2018 Apr;137(4):293-303. doi: 10.1007/s00439-018-1882-3. Epub 2018 Apr 24.
2 Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.