Details of the Drug Combinations

General Information of This Drug (ID: DMDIYFZ)

Drug Name

Telotristat ethyl DMDIYFZ

Synonyms

Telotristat; Telotristat etiprate; LP-778902; LX-1032; LX-1606; Serotonin modulator (oral, GI disorder/hypertension/carcinoid syndrome), Lexicon; Tryptophan hydroxylase inhibitor (oral, GI disorder/hypertension/carcinoid syndrome), Lexicon

Indication

Disease Entry	ICD 11	Status	REF
Carcinoid syndrome	5B10	Approved	[1]
Carcinoid syndrome diarrhea	DA90.0	Approved	[2]
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Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

2 Clinical Trial Drug Combination(s) Consisting of This drug

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Omeprazole + Telotristat ethyl	DC8ZUTA	Omeprazole	Drug-drug Interaction	[3]
Telotristat ethyl + Famotidine	DCJK72Y	Famotidine	Drug-drug Interaction	[3]
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References

1	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
2	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2018
3	ClinicalTrials.gov (NCT03302845) A Phase 1 Study to Evaluate the Effects of Omeprazole and Famotidine on the Absorption of Telotristat Ethyl in Healthy Subjects