Details of the Drug Combinations

General Information of This Drug (ID: DMDOCNW)

Drug Name

E-7050 DMDOCNW

Synonyms

C-Met and VEGF-2 tyrosine kinase inhibitor (oral, cancer), Eisai

Indication

Disease Entry	ICD 11	Status	REF
Head and neck cancer	2D42	Phase 1	[1]
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Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

1 Clinical Trial Drug Combination(s) Consisting of This drug

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Lenvatinib + E-7050	DCL2R70	Lenvatinib	Advanced Solid Tumors	[2]
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References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7956).
2	ClinicalTrials.gov (NCT01433991) A Study of E7050 in Combination With E7080 in Participants With Advanced Solid Tumors (Dose Escalation) and in Participants With Recurrent Glioblastoma or Unresectable Stage III or Stage IV Melanoma After Prior Systemic Therapy (Expansion Cohort and Phase 2)