Details of the Drug Combinations

General Information of This Drug (ID: DMDVP3B)

Drug Name
Pregabalin   DMDVP3B
Synonyms Pregabalin CR; Pregabalin (controlled-release, oral); Pregabalin (controlled-release, oral), Pfizer
Indication
Disease Entry ICD 11 Status REF
Chronic obstructive pulmonary disease CA22 Approved [1]
Epilepsy 8A60-8A68 Approved [2]
Pain MG30-MG3Z Approved [2]
Postherpetic neuralgia 1E91.5 Approved [2]
Vulvodynia N.A. Approved [2]
Chronic pain MG30 Investigative [2]
Neuralgia N.A. Investigative [2]
⏷ Show the Full List of Indication(s)
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

21 Clinical Trial Drug Combination(s) Consisting of This drug
DrugCom Name DrugCom ID Component Drug Indication REF
Duloxetine + Pregabalin DCH4EHW Duloxetine Central Sensitisation [3]
Duloxetine + Pregabalin DCB5CMJ Duloxetine Fibromyalgia [4]
Pregabalin + Morphine DC1P69V Morphine Intervertebral Disk Displacement [5]
Pregabalin + Diphenhydramine DCBFZP3 Diphenhydramine Lumbar Spinal Stenosis [6]
Pregabalin + Oxycodone DCBT4CD Oxycodone Cancer [7]
Pregabalin + Propofol DCHCLMZ Propofol Pain [8]
Pregabalin + Tramadol DCOAPPT Tramadol Diabetic Polyneuropathy [9]
Pregabalin + Remifentanil DCRS086 Remifentanil Pain [10]
Pregabalin + Morphine DCYN3NZ Morphine Postoperative Pain [11]
Pregabalin + Acetaminophen DCIHZJO Acetaminophen Postoperative Pain [12]
Pregabalin + Ketorolac DC44LL8 Ketorolac Pain, Postoperative [13]
Pregabalin + Acetaminophen DCPU7B9 Acetaminophen Postoperative Pain [14]
Citalopram + Pregabalin DCWOFP5 Citalopram Burning Mouth Syndrome [15]
Ketamine + Pregabalin DCVZAE6 Ketamine Phantom Pain [16]
Paroxetine + Pregabalin DCUVLDM Paroxetine Burning Mouth Syndrome [15]
Pregabalin + Pregabalin DCEBLWL Pregabalin Partial Seizures [17]
Pregabalin + Escitalopram DC3T2WJ Escitalopram Burning Mouth Syndrome [15]
Sertraline + Pregabalin DC13LRL Sertraline Burning Mouth Syndrome [15]
Vortioxetine + Pregabalin DCM3LDS Vortioxetine Burning Mouth Syndrome [15]
Limaprost + Pregabalin DCN645Y Limaprost Neurologic Claudication in Patients With Lumbar Spinal Stenosis [18]
Pregabalin + Ondansetron DCIR09J Ondansetron Anxiety [19]
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⏷ Show the Full List of 21 DrugCom(s)

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5484).
2 Pregabalin FDA Label
3 ClinicalTrials.gov (NCT05020600) The Effect of Central Sensitization on Treatment Response in Patients With Fibromyalgia
4 ClinicalTrials.gov (NCT01268631) Mechanism-based Choice of Therapy: Can Treatments Success in Fibromyalgia Patients be Coupled to Psychophysical Pain Modulation Profile?
5 ClinicalTrials.gov (NCT00353704) Analgetic and Anxiolytic Effect of Preoperative Pregabalin
6 ClinicalTrials.gov (NCT00638443) Lumbar Stenosis Outcomes Research (LUSTOR)
7 ClinicalTrials.gov (NCT00637975) Oxycodone and Pregabalin for the Treatment of Oncological Neuropathic Pain
8 ClinicalTrials.gov (NCT02668094) The Effect of Pregabalin on Pain of Propofol Injection
9 ClinicalTrials.gov (NCT01116531) Efficacy, Safety, Tolerability and Pharmacokinetics of Concomitant Administration of Tramadol With Duloxetine or Pregabalin
10 ClinicalTrials.gov (NCT01419405) Pregabalin and Remifentanil - Analgesia and Ventilation
11 ClinicalTrials.gov (NCT01940224) Evaluation of Preoperative Use of Pregabalin on Postoperative Analgesia After Laparoscopic Colorectal Surgery
12 ClinicalTrials.gov (NCT04265456) A Phase 1 Study to Evaluate Pregabalin and Acetaminophen in Healthy Volunteers
13 ClinicalTrials.gov (NCT03669081) Study Evaluating the Effects of Toradol and Lyrica for Pain Control After Donor Nephrectomy
14 ClinicalTrials.gov (NCT04495283) A Phase 2 Study to Evaluate Pregabalin and Acetaminophen Compared to Acetaminophen and Placebo in Subjects Undergoing Bunionectomy
15 ClinicalTrials.gov (NCT06025474) Comparison of Vortioxetine Versus Other Antidepressants With Pregabalin Augmentation in Burning Mouth Syndrome
16 ClinicalTrials.gov (NCT02311777) Pre-operative Pregabalin and Ketamine to Prevent Phantom Pain
17 ClinicalTrials.gov (NCT01262677) Once-A-Day Pregabalin For Partial Seizures
18 ClinicalTrials.gov (NCT01888536) A Study to Evaluate Efficacy of Opast Tabletfor Neurologic Claudication in Patients With Lumbar Spinal Stenosis
19 ClinicalTrials.gov (NCT05221151) Melatonin vs Pregabalin for Anxiolysis and Sedation