Details of the Drug Combinations

General Information of This Drug (ID: DMEJKRF)

Drug Name

Motexafin gadolinium DMEJKRF

Synonyms

Xcytrin; Gadolinium texaphyrin; GdT2B2; GD-Tex; Motexafin gadolinium (USAN); PCI-0120; Xcytrin (TN)

Indication

Disease Entry	ICD 11	Status	REF
Brain cancer	2A00	Approved	[1]
Human immunodeficiency virus infection	1C62	Phase 3	[2]
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Therapeutic Class

Anticancer Agents

Drug Type

Small molecular drug

Structure

3D MOL is unavailable

2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

1 Clinical Trial Drug Combination(s) Consisting of This drug

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Motexafin gadolinium + Carboplatin	DCDH4ZU	Carboplatin	Stage IIIA Non-small Cell Lung Cancer	[3]
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References

1	Photodynamic therapy: applications in atherosclerotic vascular disease with motexafin lutetium. Catheter Cardiovasc Interv. 2002 Nov;57(3):387-94.
2	Mechanism of inhibition of ribonucleotide reductase with motexafin gadolinium (MGd). Biochem Biophys Res Commun. 2009 Feb 13;379(3):775-9.
3	ClinicalTrials.gov (NCT00005065) Chemotherapy, Radiation Therapy, and Surgery in Treating Patients With Stage IIIA Non-small Cell Lung Cancer