Details of the Drug Combinations

General Information of This Drug (ID: DMGC5DB)

Drug Name
Ciprofibrate   DMGC5DB
Synonyms
Ciprofibrato; Ciprofibratum; Ciprol; Hiperlipen; Hyperlipen; Lipanor; Modalim; Oroxadin; Sanofi Synthelabo brand of ciprofibrate; Sanofi Winthrop brand of ciprofibrate; C 0330; WIN 35833; Ciprofibrato [INN-Spanish]; Ciprofibratum [INN-Latin]; Win 35,833; Win-35833; Ciprofibrate (USAN/INN); Ciprofibrate [USAN:BAN:INN]; 2-(4-(2,2-Dichlorocyclopropyl)phenoxy)2-methylpropanoic acid; 2-(p-(2,2-Dichlorocyclopropyl)phenoxy)-2-methylpropionic acid; 2-[4-(2,2-Dichlorocyclopropyl)phenoxy]-2-methylpropanoic acid; 2-[p-(2,2-Dichlorocyclopropyl)phenoxy]-2-methylpropanoic acid; 2-{4-[2,2-dichlorocyclopropyl]phenoxy}-2-methylpropanoic acid; 2-{[4-(2,2-dichlorocyclopropyl)phenyl]oxy}-2-methylpropanoic acid
Indication
Disease Entry ICD 11 Status REF
Hyperlipoproteinemia 5C80 Approved [1]
Therapeutic Class
Anticancer Agents
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

58 Investigative Drug Combination(s) Consisting of This drug
Normalized Drug Combination Synergy Score
Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.
DrugCom Name DrugCom ID Component Drug Indication REF
Acetohexamide + Ciprofibrate DCMHI15 Acetohexamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Acetohydroxamic Acid + Ciprofibrate DCH1933 Acetohydroxamic Acid Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Arfolitixorin + Ciprofibrate DCS4DW4 Arfolitixorin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Armodafinil + Ciprofibrate DCNKBEN Armodafinil Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Asenapine + Ciprofibrate DCGWKXX Asenapine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Bepridil + Ciprofibrate DCTNQIP Bepridil Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
BIO-300 + Ciprofibrate DCAAN8M BIO-300 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Bortezomib + Ciprofibrate DCJ7NW5 Bortezomib Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Brincidofovir + Ciprofibrate DCBLAUS Brincidofovir Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Cilastatin + Ciprofibrate DCGTP2O Cilastatin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Ciprofibrate + Sertraline DCTTQN1 Sertraline Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Ciprofibrate + Acetazolamide DCUCBEQ Acetazolamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Ciprofibrate + Tindamax DCSF9YA Tindamax Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Ciprofibrate + Triapine DCUNDJ6 Triapine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Ciprofibrate + Palonosetron DC1A0WG Palonosetron Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Ciprofibrate + Testosterone cypionate DC60IIJ Testosterone cypionate Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Ciprofibrate + Docetaxel DC7PMIN Docetaxel Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Ciprofibrate + PHA-739358 DCC3YPZ PHA-739358 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Ciprofibrate + Triflupromazine DCID53B Triflupromazine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Ciprofibrate + Imatinib DCL3AQM Imatinib Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Ciprofibrate + Pramipexole DC0RET4 Pramipexole Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Ciprofibrate + Tropisetron DCUQZSB Tropisetron Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Ciprofibrate + Mesalazine DCI0KT6 Mesalazine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Ciprofibrate + Maprotiline DCHF3NA Maprotiline Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Ciprofibrate + Brincidofovir DCXQ9QH Brincidofovir Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Ciprofibrate + Vorinostat DCIQ1ED Vorinostat Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Ciprofibrate + Cerivastatin DC60CRY Cerivastatin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Ciprofibrate + Atovaquone DCZWVRI Atovaquone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Ciprofibrate + Cytarabine DCX2CR5 Cytarabine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Diazoxide + Ciprofibrate DCR487P Diazoxide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Doxorubicin + Ciprofibrate DC1509U Doxorubicin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Endoxifen + Ciprofibrate DCBF6I8 Endoxifen Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Epinephrine + Ciprofibrate DCOS4AK Epinephrine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Etomidate + Ciprofibrate DCDR0QT Etomidate Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Ezetimibe + Ciprofibrate DC8B2SQ Ezetimibe Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Fenoprofen + Ciprofibrate DCMTV55 Fenoprofen Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Fibrates + Ciprofibrate DC5SHZ5 Fibrates Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Fosfomycin + Ciprofibrate DCVWXWU Fosfomycin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Gefitinib + Ciprofibrate DCTE2UO Gefitinib Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Hydralazine + Ciprofibrate DCIP8UK Hydralazine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Hyodeoxycholic acid + Ciprofibrate DCV39PE Hyodeoxycholic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Idarubicin + Ciprofibrate DC9R5FS Idarubicin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
JZL195 + Ciprofibrate DC9J2PA JZL195 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Mefloquine + Ciprofibrate DC97GFD Mefloquine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Methotrexate + Ciprofibrate DCH04VF Methotrexate Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Mycophenolic acid + Ciprofibrate DCHHKD2 Mycophenolic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Naltrexone + Ciprofibrate DCN8CV2 Naltrexone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Pentostatin + Ciprofibrate DCCSGCP Pentostatin Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Pinacidil + Ciprofibrate DCWRSW7 Pinacidil Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
PMID28460551-Compound-2 + Ciprofibrate DC3XOUN PMID28460551-Compound-2 Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Probenecid + Ciprofibrate DCH0B6F Probenecid Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Pyrazinamide + Ciprofibrate DCVANTE Pyrazinamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Rufinamide + Ciprofibrate DCZVYUF Rufinamide Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Testolactone + Ciprofibrate DCIH7CX Testolactone Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Tiagabine + Ciprofibrate DC9JGB9 Tiagabine Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Topotecan + Ciprofibrate DC058WK Topotecan Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Trihexyphenidyl + Ciprofibrate DCRD5FD Trihexyphenidyl Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
Trioxsalen + Ciprofibrate DC4EAB1 Trioxsalen Chronic myelogenous leukemia (Cell Line: KBM-7) [2]
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⏷ Show the Full List of 58 DrugCom(s)

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3438).
2 Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.
3 Loss of function mutations in VARS encoding cytoplasmic valyl-tRNA synthetase cause microcephaly, seizures, and progressive cerebral atrophy.Hum Genet. 2018 Apr;137(4):293-303. doi: 10.1007/s00439-018-1882-3. Epub 2018 Apr 24.