Details of the Drug Combinations

General Information of This Drug (ID: DMHNDTW)

Drug Name

aminooxyacetic acid DMHNDTW

Synonyms

Aminooxyacetic acid; (aminooxy)acetic acid; 2-(Aminooxy)acetic acid; AOAA; carboxymethoxylamine; 645-88-5; Carboxymethoxyamine; ACETIC ACID, (AMINOOXY)-; Aminooxyacetate; Aminooxy-acetic acid; (Carboxymethoxy)amine; (o-Carboxymethyl)hydroxylamine; aminoxyacetic acid; UNII-14I68GI3OQ; BRN 0878238; C2H5NO3; 14I68GI3OQ; U 7524; NQRKYASMKDDGHT-UHFFFAOYSA-N; u-7524; AOA; Aminooxyacetic acid hemihydrochloride; Carboxymethoxylamine hemihydrochloride; aminoxy-acetic acid; amino-oxyacetic acid; AOA hemihydrochloride; 2-aminooxyacetic acid; AOAA

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]
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Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

3 Clinical Trial Drug Combination(s) Consisting of This drug

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Aminooxyacetic acid + Temozolomide	DC86O3L	Temozolomide	Unspecified Adult Solid Tumor, Protocol Specific	[2]
Aminooxyacetic acid + Fludarabine	DCD74NV	Fludarabine	Adult Nasal Type Extranodal NK/T-cell Lymphoma	[3]
Aminooxyacetic acid + Pemetrexed	DC8M2IK	Pemetrexed	Advanced Malignant Solid Neoplasm	[4]
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References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5136).
2	ClinicalTrials.gov (NCT00892385) Methoxyamine and Temozolomide in Treating Patients With Advanced Solid Tumors
3	ClinicalTrials.gov (NCT01658319) Methoxyamine and Fludarabine Phosphate in Treating Patients With Relapsed or Refractory Hematologic Malignancies
4	ClinicalTrials.gov (NCT02535312) Methoxyamine, Cisplatin, and Pemetrexed Disodium in Treating Patients With Advanced Solid Tumors or Mesothelioma That Cannot Be Removed by Surgery or Mesothelioma That Is Refractory to Pemetrexed Disodium and Cisplatin or Carboplatin