Details of the Drug Combinations

General Information of This Drug (ID: DMI7FVQ)

Drug Name

Metyrapone DMI7FVQ

Synonyms

MYT; Mepyrapone; Metapirone; Metapyron; Methapyrapone; Methbipyranone; Methopirapone; Methopyrapone; Methopyrinine; Methopyrone; Metirapona; Metopiron; Metopirone; Metopyrone; Metroprione; Metyrapon; Metyraponum; Alliance Brand of Metyrapone; Metyrapone Alliance Brand; Metyrapone Novartis Brand; Novartis Brand of Metyrapone; Su 4885; METOPIRONE (TN); Metirapona [INN-Spanish]; Metopirone (TN); Metyraponum [INN-Latin]; Su-4885; Metyrapone (JP15/USP/INN); Metyrapone [USAN:INN:BAN:JAN]; 1,2-Di-3-pyridyl-2-methyl-1-propanone; 2-Methyl-1,2-bis(3-pyridyl)-1-propanone; 2-Methyl-1,2-di-3-pyridinyl-1-propanone; 2-Methyl-1,2-di-3-pyridyl-1-propanone; 2-methyl-1,2-dipyridin-3-yl-propan-1-one; 2-methyl-1,2-dipyridin-3-ylpropan-1-one

Indication

Disease Entry	ICD 11	Status	REF
Cushing disease	5A70	Approved	[1]
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Therapeutic Class

Antimetabolites

Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

2 Clinical Trial Drug Combination(s) Consisting of This drug

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Metyrapone + Oxazepam	DCFEJH6	Oxazepam	Cocaine Dependence	[2]
Metyrapone + Hydrocortisone	DC4W0T5	Hydrocortisone	Glucocorticoid Effect	[3]
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References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5224).
2	ClinicalTrials.gov (NCT00567814) A Placebo-Controlled Study of a Combination of Metyrapone and Oxazepam in Cocaine Addiction
3	ClinicalTrials.gov (NCT05167084) Acute Consequences Of Food-induced Glucocorticoid Secretion In Healthy Individuals