Details of the Drug Combinations

General Information of This Drug (ID: DMJTU8D)

Drug Name

OGX-427 DMJTU8D

Indication

Disease Entry	ICD 11	Status	REF
Bladder cancer	2C94	Phase 2	[1]
Breast cancer	2C60-2C65	Phase 2	[1]
Lung cancer	2C25.0	Phase 2	[1]
Ovarian cancer	2C73	Phase 2	[1]
Prostate cancer	2C82.0	Phase 2	[1]
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Therapeutic Class

Antisense

Drug Type

Antisense drug

Structure

3D MOL is unavailable

2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

1 Investigative Drug Combination(s) Consisting of This drug

Normalized Drug Combination Synergy Score

Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
OGX-427 + Paclitaxel	DCTMFNE	Paclitaxel	Lung cancer; Prostate cancer; Bladder cancer; Ovarian cancer; Breast cancer (Cell Line: .)	[2]
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References

1	ClinicalTrials.gov (NCT02423590) Study of Gemcitabine/Carboplatin First-line Chemotherapy +/- Apatorsen in Advanced Squamous Cell Lung Cancers. U.S. National Institutes of Health.
2	FDA Drug Development and Drug Interactions