Details of the Drug Combinations

General Information of This Drug (ID: DMK3TMD)

Drug Name
PMID25656651-Compound-7   DMK3TMD
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

2 Investigative Drug Combination(s) Consisting of This drug
Normalized Drug Combination Synergy Score
Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.
DrugCom Name DrugCom ID Component Drug Indication REF
PMID25656651-Compound-7 + Panobinostat DCKCTT7 Panobinostat Diffuse intrinsic pontine glioma (Cell Line: DIPG25) [1]
PMID25656651-Compound-7 + Mitomycin DC2DLIS Mitomycin Diffuse large B cell lymphoma (Cell Line: TMD8) [1]
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2 Clinical Trial Drug Combination(s) Consisting of This drug
DrugCom Name DrugCom ID Component Drug Indication REF
Eribulin + PMID25656651-Compound-7 DCQCAR3 Eribulin Breast Cancer [2]
PMID25656651-Compound-7 + Paclitaxel DC4FEFD Paclitaxel Breast Cancer [2]
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References

1 Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.
2 ClinicalTrials.gov (NCT02824575) Rebastinib Plus Antitubulin Therapy With Paclitaxel or Eribulin in Metastatic Breast Cancer