Details of the Drug Combinations

General Information of This Drug (ID: DMMUFKM)

Drug Name

Colesevelam DMMUFKM

Synonyms

CholestaGel; Welchol; Colesevelam hydrochloride; Welchol DM; GT31-104; GT31-104HB

Indication

Disease Entry	ICD 11	Status	REF
Hypercholesterolaemia	5C80.0	Approved	[1]
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Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

5 Clinical Trial Drug Combination(s) Consisting of This drug

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Colesevelam + Acetaminophen	DCAUFKS	Acetaminophen	To Assess the Impact of Bile Acids on Human Glukagon-like-peptide-1 Secretion	[2]
Metformin + Colesevelam	DCI79H1	Metformin	Type 2 Diabetes	[3]
HKI-272 + Colesevelam	DCUX4QR	HKI-272	Early-stage Breast Cancer	[4]
Clonidine + Colesevelam	DCIVMRY	Clonidine	Fecal Incontinence	[5]
Colesevelam + Chenodiol	DCBU4FI	Chenodiol	Severe Obesity	[6]
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References

1	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
2	ClinicalTrials.gov (NCT01656057) The Impact of Gall Bladder Emptying and Bile Acids on the Human GLP-1-secretion
3	ClinicalTrials.gov (NCT00951899) The Effect of Welchol on Glucose Metabolism in Type 2 Diabetics
4	ClinicalTrials.gov (NCT05252988) Three Antidiarrheal Strategies in HER2+/HR+ Early Breast Cancer Patients Treated With Extended Adjuvant Neratinib
5	ClinicalTrials.gov (NCT02628626) A Study of Colesevelam in Fecal Incontinence
6	ClinicalTrials.gov (NCT02952963) Effect of Bile Acids and Bile Acid Sequstrants on GLP-1 Secretion After Roux-en-Y Gastric Bypass