Details of the Drug Combinations

General Information of This Drug (ID: DMPGR1E)

Drug Name

Clascoterone DMPGR1E

Synonyms

CB-03-01

Indication

Disease Entry	ICD 11	Status	REF
Acne vulgaris	ED80	Approved	[1]
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Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

72 Investigative Drug Combination(s) Consisting of This drug

Normalized Drug Combination Synergy Score

Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Acamprosate + Clascoterone	DCOILLV	Acamprosate	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Acitretin + Clascoterone	DCO9PFF	Acitretin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Artemisinin + Clascoterone	DC0CRWW	Artemisinin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Asenapine + Clascoterone	DC08RN2	Asenapine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Bortezomib + Clascoterone	DCSP2BU	Bortezomib	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Brincidofovir + Clascoterone	DCLCFG6	Brincidofovir	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Clascoterone + Ribavirin-TP	DCI4QKT	Ribavirin-TP	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Clascoterone + Bepridil	DCE4CS8	Bepridil	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Clascoterone + Aliskiren	DCUFHGE	Aliskiren	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Clascoterone + PMID28460551-Compound-2	DCDHI23	PMID28460551-Compound-2	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Clascoterone + Sivelestat	DCOTXWB	Sivelestat	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Clascoterone + Triapine	DCX40MA	Triapine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Clascoterone + Metyrosine	DCAWT7J	Metyrosine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Clascoterone + Terameprocol	DCPIUK7	Terameprocol	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Clascoterone + Chlorzoxazone	DCX9J74	Chlorzoxazone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Clascoterone + K-134	DC2OEJC	K-134	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Clascoterone + Memantine	DCMQ4K7	Memantine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Clascoterone + Metformin	DCOENWL	Metformin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Clascoterone + Phenprocoumon	DCCMBV7	Phenprocoumon	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Clascoterone + Fibrates	DCB9O7Z	Fibrates	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Clascoterone + PFK-158	DCPWWJ3	PFK-158	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Clascoterone + Tolvaptan	DCR9DBO	Tolvaptan	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Clascoterone + Triflupromazine	DC6FWHO	Triflupromazine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Clascoterone + BIO-300	DCDUWLF	BIO-300	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Clascoterone + Eflornithine	DCO1MVH	Eflornithine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Clascoterone + PF-02545920	DC5MJ1C	PF-02545920	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Clascoterone + Allopurinol	DC8V8M4	Allopurinol	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Clascoterone + Idarubicin	DCOKUXP	Idarubicin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Clascoterone + Idarubicin	DCUYZ5D	Idarubicin	Glioblastoma? (Cell Line: T98G)	[2]
Clascoterone + BRL-15572	DC2WXPQ	BRL-15572	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Clascoterone + Linagliptin	DCU2FLN	Linagliptin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Clascoterone + Methylene blue	DCAGOL1	Methylene blue	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Clascoterone + Olanzapine	DCM2MCI	Olanzapine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Clascoterone + Maprotiline	DC8VLN3	Maprotiline	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Clascoterone + Cisatracurium	DCFQ8YB	Cisatracurium	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Clascoterone + Fosfomycin	DCZHCTG	Fosfomycin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Clascoterone + Cerivastatin	DCVHVWX	Cerivastatin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Clascoterone + Metaxalone	DCF0IJ5	Metaxalone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Clascoterone + Raltegravir	DCFX7ZP	Raltegravir	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Clascoterone + Albendazole	DCQCO22	Albendazole	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Clascoterone + AS-1949490	DCPATV2	AS-1949490	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Cytarabine + Clascoterone	DC66GY5	Cytarabine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Dantrolene + Clascoterone	DCEV30Q	Dantrolene	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Darunavir + Clascoterone	DCVJK9Q	Darunavir	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Dopamine + Clascoterone	DCYVG6D	Dopamine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Doxorubicin + Clascoterone	DC3CRDS	Doxorubicin	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Emetine + Clascoterone	DC10YY2	Emetine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Ethinyl estradiol + Clascoterone	DCAQ3T8	Ethinyl estradiol	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
ETHISTERONE + Clascoterone	DCNXCQJ	ETHISTERONE	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Etonogestrel + Clascoterone	DCR7OVM	Etonogestrel	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Everolimus + Clascoterone	DC92EHU	Everolimus	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Fenoprofen + Clascoterone	DCAPLBZ	Fenoprofen	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
GYKI-52466 + Clascoterone	DC5TZCH	GYKI-52466	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Imatinib + Clascoterone	DC3LGXG	Imatinib	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Itraconazole + Clascoterone	DC6QV2N	Itraconazole	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
L-165041 + Clascoterone	DCKKSS0	L-165041	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Lithium Citrate + Clascoterone	DCVWYNL	Lithium Citrate	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Mecamylamine + Clascoterone	DCAV71X	Mecamylamine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Mefloquine + Clascoterone	DC9RYA8	Mefloquine	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Miglustat + Clascoterone	DCH0KB7	Miglustat	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Mycophenolic acid + Clascoterone	DC9JCZX	Mycophenolic acid	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Naltrexone + Clascoterone	DC23AXG	Naltrexone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Niclosamide + Clascoterone	DC24DDC	Niclosamide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Olmesartan medoxomil + Clascoterone	DCQDD6N	Olmesartan medoxomil	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Pyrazinamide + Clascoterone	DCW6OUM	Pyrazinamide	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Sertraline + Clascoterone	DCX37SE	Sertraline	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Tamoxifen + Clascoterone	DCQHKB5	Tamoxifen	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Testolactone + Clascoterone	DC3SGDK	Testolactone	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Theophylline + Clascoterone	DCPJLZQ	Theophylline	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Tindamax + Clascoterone	DC0S3YZ	Tindamax	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
Vorinostat + Clascoterone	DCE2UVH	Vorinostat	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
VR-776 + Clascoterone	DCBECY6	VR-776	Chronic myelogenous leukemia (Cell Line: KBM-7)	[2]
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⏷ Show the Full List of 72 DrugCom(s)

References

1	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health Human Services. 2020
2	Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.