Details of the Drug Combinations

General Information of This Drug (ID: DMQ8FR2)

Drug Name
Prednisolone   DMQ8FR2
Synonyms
Nanocort; Prednisolone (injectable liposome formulation, rheumatoid arthritis); Prednisolone (injectable liposome formulation, rheumatoid arthritis), Enceladus; Prednisolone (injectable liposome formulation, rheumatoid arthritis), Galapagos
Indication
Disease Entry ICD 11 Status REF
Acute adrenal insufficiency N.A. Approved [1]
Acute asthma CA23 Approved [1]
Addison disease 5A74.0 Approved [1]
Allergic rhinitis CA08.0 Approved [1]
Angioedema 4A00.15 Approved [1]
Aspiration pneumonitis N.A. Approved [1]
Autoimmune haemolytic anaemia 3A20 Approved [1]
Blepharoconjunctivitis N.A. Approved [1]
Bursitis N.A. Approved [1]
Cerebral edema 8D60.1 Approved [1]
Chronic graft versus host disease N.A. Approved [1]
Congenital adrenal hyperplasia 5A71.01 Approved [1]
Corneal abrasion NA06.4 Approved [1]
Corneal ulcer 9A76 Approved [1]
Crohn disease DD70 Approved [1]
Dacryocystitis N.A. Approved [1]
Demodex blepharitis 1G07 Approved [1]
Dermatitis herpetiformis EB44 Approved [1]
Diamond-Blackfan anemia N.A. Approved [1]
Disorder of orbital region N.A. Approved [1]
Epicondylitis N.A. Approved [1]
Erythema multiforme N.A. Approved [1]
Exanthem N.A. Approved [1]
Fever MG26 Approved [1]
Granuloma annulare N.A. Approved [1]
Hypersensitivity pneumonitis N.A. Approved [1]
Inflammatory bowel disease DD72 Approved [1]
Ischemia-reperfusion injury DB98.B Approved [1]
Keratitis N.A. Approved [1]
Leukemia N.A. Approved [1]
Lupus nephritis 4A40.0Y Approved [1]
Microscopic polyangiitis N.A. Approved [1]
Miliary tuberculosis N.A. Approved [1]
Mycosis fungoides 2B01 Approved [1]
Myeloproliferative neoplasm 2A20 Approved [1]
Pneumocystis pneumonia CA40.20 Approved [1]
Polymyalgia rheumatica N.A. Approved [1]
Primary cutaneous T-cell lymphoma N.A. Approved [1]
Psoriasis EA90 Approved [1]
Psoriatic arthritis FA21 Approved [1]
Rheumatic heart disease N.A. Approved [1]
Rosacea ED90.0 Approved [1]
Sarcoidosis 4B20.5 Approved [1]
Serum sickness N.A. Approved [1]
Severe asthma CA23 Approved [1]
Skin disease EA00-EM0Z Approved [1]
Solid tumour/cancer 2A00-2F9Z Approved [2]
Sympathetic ophthalmia N.A. Approved [1]
Systemic lupus erythematosus 4A40.0 Approved [1]
Ulcerative colitis DD71 Approved [1]
Multiple sclerosis 8A40 Phase 3 [3]
Acquired thrombocytopenia N.A. Investigative [1]
Asthma CA23 Investigative [1]
Beta-thalassemia major N.A. Investigative [1]
Classic Hodgkin lymphoma N.A. Investigative [1]
Follicular lymphoma 2A80 Investigative [1]
Iridocyclitis N.A. Investigative [1]
Sjogren syndrome 4A43.20 Investigative [1]
Synovitis N.A. Investigative [1]
Uveitis 9A96.Z Investigative [1]
⏷ Show the Full List of Indication(s)
Therapeutic Class
Anticancer Agents
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

1 Investigative Drug Combination(s) Consisting of This drug
Normalized Drug Combination Synergy Score
Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.
DrugCom Name DrugCom ID Component Drug Indication REF
Prednisolone + Idarubicin DCUX4SM Idarubicin Glioblastoma? (Cell Line: T98G) [4]
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45 Clinical Trial Drug Combination(s) Consisting of This drug
DrugCom Name DrugCom ID Component Drug Indication REF
ABIRATERONE + Prednisolone DCIP21R ABIRATERONE Prostate Cancer [5]
Azathioprine + Prednisolone DCDS0G1 Azathioprine Lupus Nephritis [6]
Azathioprine + Prednisolone DC3EEZD Azathioprine Lupus Nephritis [6]
Azathioprine + Prednisolone DC8HTYE Azathioprine Crohn's Disease [7]
Azathioprine + Prednisolone DCOHCUE Azathioprine Colitis, Ulcerative [8]
Baricitinib + Prednisolone DCIVXS6 Baricitinib IgG4-related Disease With Eosinophilia [9]
Cabazitaxel + Prednisolone DC2PSQP Cabazitaxel Prostate Cancer [10]
Dexamethasone + Prednisolone DCI70YL Dexamethasone Urticaria [11]
GS-4997 + Prednisolone DCPWXEJ GS-4997 Severe Alcoholic Hepatitis [12]
Methotrexate + Prednisolone DC1Q8UQ Methotrexate Polymyositis [13]
Methotrexate + Prednisolone DCLRI0S Methotrexate Erythema Nodosum Leprosum [14]
Methylprednisolone + Prednisolone DC7RCGW Methylprednisolone Immune Reconstitution Inflammatory Syndrome [15]
Mycophenolate mofetil + Prednisolone DC20QJN Mycophenolate mofetil Lupus Nephritis [6]
Mycophenolate mofetil + Prednisolone DCQ65OC Mycophenolate mofetil Heart Transplantation [16]
Mycophenolate mofetil + Prednisolone DCRH3VV Mycophenolate mofetil Lupus Nephritis [17]
Prednisolone + Hydroxychloroquine DC2LI4D Hydroxychloroquine Lupus Nephritis [6]
Prednisolone + Cyclosporin A DCMINDQ Cyclosporin A Lupus Nephritis [6]
Prednisolone + Acetylcysteine DC5VDJ4 Acetylcysteine Drug Induced Liver Injury [18]
Prednisolone + Azithromycin DC7JDMN Azithromycin Asthma [19]
Prednisolone + Mycophenolic acid DCBRB5O Mycophenolic acid Uveitis, Intermediate [20]
Prednisolone + Hydroxychloroquine DCEGATO Hydroxychloroquine Lupus Nephritis [6]
Propranolol + Prednisolone DCEWV0P Propranolol Hemangioma [21]
Aspirin + Prednisolone DC2S2NT Aspirin Infertility [22]
Dexamethasone + Prednisolone DCQEH9V Dexamethasone Postoperative Pain [23]
GS-4997 + Prednisolone DC2HNH9 GS-4997 Alcoholic Hepatitis (AH) [24]
Methylprednisolone + Prednisolone DCCH6H1 Methylprednisolone Cerebral Radiation Necrosis [25]
Mycophenolate mofetil + Prednisolone DCIAZ0S Mycophenolate mofetil Lupus Nephritis [26]
Prednisolone + Tacrolimus DC8M9Z3 Tacrolimus Sjogren Syndrome With Other Organ Involvement [27]
Prednisolone + Hydroxychloroquine DCP777J Hydroxychloroquine Inflammatory Cardiomyopathy [28]
Doxycycline + Prednisolone DCECM0C Doxycycline Nasal Polyps [29]
Hydrocortisone + Prednisolone DCQ5DOY Hydrocortisone Adrenal Insufficiency [30]
Itraconazole + Prednisolone DC0XWW6 Itraconazole Allergic Bronchopulmonary Aspergillosis [31]
Ofloxacin + Prednisolone DCARCU8 Ofloxacin Glaucoma [32]
Ofloxacin + Prednisolone DCIJN08 Ofloxacin Open Angle Glaucoma [33]
Ofloxacin + Prednisolone DCMY8I1 Ofloxacin Open Angle Glaucoma [33]
Ofloxacin + Prednisolone DCN96QR Ofloxacin Glaucoma [32]
Prednisolone + Losartan DC2LRUE Losartan COVID-19 Associated Cardiac Involvement [34]
Upadacitinib + Prednisolone DCVO48C Upadacitinib Takayasu Arteritis (TAK) [35]
Betamethasone + Prednisolone DCMRF6F Betamethasone Vestibular Diseases [36]
Dapsone + Prednisolone DC9T1FD Dapsone Bullous Pemphigoid [37]
Lisinopril + Prednisolone DC3BBMB Lisinopril Glomerulonephritis [38]
Prednisolone + Apremilast DC4113E Apremilast Oral Lichen Planus [39]
Prednisolone + Leflunomide DCLUM2T Leflunomide Immunoglobulin G4 Related Sclerosing Disease [40]
Prednisolone + Nepafenac DCNRAJM Nepafenac Uveitis [41]
Prednisolone + Levofloxacin DCYI131 Levofloxacin Mycoplasma Pneumoniae Pneumonia [42]
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⏷ Show the Full List of 45 DrugCom(s)

References

1 Prednisolone FDA Label
2 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
3 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2866).
4 Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.
5 ClinicalTrials.gov (NCT01685983) A Study of Abiraterone Acetate (JNJ-212082) and Prednisolone in Patients With Advanced Prostate Cancer
6 ClinicalTrials.gov (NCT03791827) Multicenter Registry of Pediatric Lupus Nephritis in China
7 ClinicalTrials.gov (NCT00796250) Efficacy of Infliximab in the Treatment of Patients Affected by Corticodependent Crohn's Disease (P02732)
8 ClinicalTrials.gov (NCT00984568) Conventional Step-Up Versus Infliximab Monotherapy in Patients With Ulcerative Colitis (P05553)
9 ClinicalTrials.gov (NCT05781516) Baricitinib Plus Glucocorticoid for Eosinophilia in IgG4-RD
10 ClinicalTrials.gov (NCT01324583) Dose Escalation Study With Cabazitaxel in Combination With Daily Prednisolone in Patients With Hormone Refractory Prostate Cancer
11 ClinicalTrials.gov (NCT03296358) Adding a Short Burst of Corticosteroid to the Conventional Treatment of H1 Antihistamines in Emergency Department.
12 ClinicalTrials.gov (NCT03087968) Evaluation of HepQuant SHUNT to Assess Liver Disease; Substudy Within GS-US-416-2124
13 ClinicalTrials.gov (NCT00651040) Combined Treatment of Methotrexate + Glucocorticoids Versus Glucocorticoids Alone in Patients With PM and DM
14 ClinicalTrials.gov (NCT03775460) Methotrexate and Prednisolone Study in Erythema Nodosum Leprosum
15 ClinicalTrials.gov (NCT01211665) Corticosteroids for Immune Reconstitution Inflammatory Syndrome (IRIS)
16 ClinicalTrials.gov (NCT00359658) Withdrawal of Steroids, Cyclosporine A Dose Reduction and Switch to Mycophenolatmofetile After Heart Transplantation
17 ClinicalTrials.gov (NCT00425438) A Study of CellCept (Mycophenolate Mofetil) in Patients With Lupus Nephritis.
18 ClinicalTrials.gov (NCT02686385) Efficacy of N-acetylcysteine With or Without Steroids in Drug Induced Liver Injury
19 ClinicalTrials.gov (NCT01272635) Treatment of Preschool Children With Upper Respiratory Tract Illnesses Using Azythromycin and Lower Respiratory Tract Symptoms Using Oral Corticosteroids.
20 ClinicalTrials.gov (NCT01092533) Myfortic for the Treatment of Non-infectious Intermediate Uveitis
21 ClinicalTrials.gov (NCT01074437) Corticosteroids With Placebo Versus Corticosteroids With Propranolol Treatment of Infantile Hemangiomas (IH)
22 ClinicalTrials.gov (NCT03503227) The Value of Prednisolone With Aspirin Before Embryo Transfer in Intracytoplasmic Sperm Injection (ICSI) Cycles
23 ClinicalTrials.gov (NCT02401529) Effect of Steroids on Post-tonsillectomy Morbidities
24 ClinicalTrials.gov (NCT02854631) Selonsertib in Combination With Prednisolone Versus Prednisolone Alone in Participants With Severe Alcoholic Hepatitis (AH)
25 ClinicalTrials.gov (NCT03067753) Monosialoganglioside Ganglioside in Cerebral Radiation Necrosis
26 ClinicalTrials.gov (NCT02949349) Mycophenolate Mofetil Versus Azathioprine for Maintenance Therapy of Lupus Nephritis
27 ClinicalTrials.gov (NCT05694130) Tacrolimus Plus Glucocorticoid for Severe Thrombocytopenia in SS
28 ClinicalTrials.gov (NCT05961202) The Effects of Hydroxychloroquine in Patients With Inflammatory Cardiomyopathy
29 ClinicalTrials.gov (NCT05157412) Role of Doxycycline in Chronic Rhinosinusitis With Nasal Polyps
30 ClinicalTrials.gov (NCT03936517) Safety and Efficacy of Prednisolone in Adrenal Insufficiency Disease (PRED-AID Study)
31 ClinicalTrials.gov (NCT06174922) A Randomized Trial of Prednisolone, Itraconazole, or Their Combination in Allergic Bronchopulmonary Aspergillosis
32 ClinicalTrials.gov (NCT03933631) Pilocarpine Use After Kahook Goniotomy
33 ClinicalTrials.gov (NCT04005079) Pilocarpine After Combined Cataract/Trabectome Surgery
34 ClinicalTrials.gov (NCT05619653) Myocardial Protection in Patients With Post-acute Inflammatory Cardiac Involvement Due to COVID-19
35 ClinicalTrials.gov (NCT04161898) A Study to Evaluate the Efficacy and Safety of Upadacitinib in Participants With Takayasu Arteritis (TAK)
36 ClinicalTrials.gov (NCT02912182) Acute Unilateral Vestibulopathy and Corticosteroid Treatment
37 ClinicalTrials.gov (NCT05984381) Efficacy and Safety of add-on Dapsone Versus add-on Methotrexate in Patients With Bullous Pemphigoid
38 ClinicalTrials.gov (NCT04662723) Multicentre Clinical Study to Evaluate the Effect of Personalized Therapy on Patients With Immunoglobulin A Nephropathy.
39 ClinicalTrials.gov (NCT06260904) Efficacy and Safety of add-on Apremilast Versus add-on Methotrexate in Patients With Oral Lichen Planus
40 ClinicalTrials.gov (NCT02703194) Leflunomide for Maintenance of Remission in IgG4 Related Disease
41 ClinicalTrials.gov (NCT01939691) Macular Edema Nepafenac vs. Difluprednate Uveitis Trial
42 ClinicalTrials.gov (NCT02618057) Effects of Oral Steroid in Mycoplasma Pneumoniae Pneumonia