Details of the Drug Combinations | DrugMAP

General Information of This Drug (ID: DMRAFBK)

Drug Name

PF-04958242 DMRAFBK

Indication

Disease Entry	ICD 11	Status	REF
Schizophrenia	6A20	Phase 2	[1]
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Structure

3D MOL

2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

3 Clinical Trial Drug Combination(s) Consisting of This drug

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Ketamine + PF-04958242	DCW0FIZ	Ketamine	Schizophrenia	[2]
PF-04958242 + PF-04958242	DC8VJSG	PF-04958242	Schizophrenia	[3]
PF-04958242 + PF-04958242	DCIPJIR	PF-04958242	Schizophrenia	[4]
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References

1	Antibodies and venom peptides: new modalities for ion channels. Nat Rev Drug Discov. 2019 May;18(5):339-357.
2	ClinicalTrials.gov (NCT01749098) A Study To Examine The Effects Of PF-04958242 On Ketamine-Induced Cognitive Impairment In Healthy Volunteers
3	ClinicalTrials.gov (NCT01511510) Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Repeated Doses of PF-04958242 in Healthy Volunteers
4	ClinicalTrials.gov (NCT01518894) A Study To Examine The Safety, Tolerability And Pharmacokinetics Of PF-04958242 In Psychiatrically Stable Subjects With Schizophrenia