Details of the Drug Combinations

General Information of This Drug (ID: DMSMFN2)

Drug Name

GSK2140944 DMSMFN2

Synonyms

Gepotidacin

Indication

Disease Entry	ICD 11	Status	REF
Neisseria gonorrhoeae infection	1A7Z	Phase 3	[1]
Urinary tract infection	GC08	Phase 3	[2]
Acute bacterial skin infection	1C41	Phase 2	[3]
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Structure

3D MOL

2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

3 Clinical Trial Drug Combination(s) Consisting of This drug

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Cimetidine + GSK2140944	DCHWZ3E	Cimetidine	Infections, Bacterial	[4]
Digoxin + GSK2140944	DCTS3O4	Digoxin	Infections, Bacterial	[4]
Rifampicin + GSK2140944	DCH8CB0	Rifampicin	Infections, Bacterial	[4]
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References

1	ClinicalTrials.gov (NCT04010539) A Study Evaluating Efficacy and Safety of Gepotidacin Compared With Ceftriaxone Plus Azithromycin in the Treatment of Uncomplicated Urogenital Gonorrhea. U.S. National Institutes of Health.
2	ClinicalTrials.gov (NCT04020341) A Study to Evaluate Efficacy and Safety of Gepotidacin in the Treatment of Uncomplicated Urinary Tract Infection (UTI). U.S. National Institutes of Health.
3	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
4	ClinicalTrials.gov (NCT04493931) Drug-drug Interaction Study of Gepotidacin