Details of the Drug Combinations

General Information of This Drug (ID: DMTWS9E)

Drug Name

Apremilast DMTWS9E

Synonyms

Apremilast (USAN); CC-10004; N-[2-[1-(3-ethoxy-4-methoxy-phenyl)-2-methylsulfonyl-ethyl]-1,3-dioxo-isoindol-4-yl]acetamide

Indication

Disease Entry	ICD 11	Status	REF
Psoriasis vulgaris	EA90	Approved	[1]
Psoriatic arthritis	FA21	Approved	[2]
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Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

2 Clinical Trial Drug Combination(s) Consisting of This drug

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
ERITORAN + Apremilast	DCQNNKU	ERITORAN	Community-acquired Pneumonia, Influenza, COVID-19	[3]
Prednisolone + Apremilast	DC4113E	Prednisolone	Oral Lichen Planus	[4]
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References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7372).
2	Apremilast FDA Label
3	ClinicalTrials.gov (NCT02735707) Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired Pneumonia
4	ClinicalTrials.gov (NCT06260904) Efficacy and Safety of add-on Apremilast Versus add-on Methotrexate in Patients With Oral Lichen Planus