Details of the Drug Combinations

General Information of This Drug (ID: DMUI0CH)

Drug Name
Tobramycin   DMUI0CH
Synonyms
Aktob; Brulamycin; Distobram; Gotabiotic; NEBRAMYCIN; Nebcin; Nebicin; Obracin; Obramycin; Sybryx; TOY; Tenebrimycin;Tenemycin; Tobacin; Tobi; Tobracin; Tobradex; Tobradistin; Tobralex; Tobramaxin; Tobramicin; Tobramicina; Tobramitsetin; Tobramycetin; Tobramycine; Tobramycinum; Tobrased; Tobrasone; Tobrex; Deoxykanamycin B; Nebramycin VI; TOBRAMYCIN SULFATE; Tobramycin for Inhalation; Tobramycin solution for inhalation; A 12253A; Lilly 47663; NF 6; Nebramycin 6; Nebramycin factir 6; Nebramycin factor 6; Nebcin (Sulfate); SPRC-AB01; TobraDex (TN); Tobracin (TN); Tobramicina [INN-Spanish]; Tobramycin, Free Base; Tobramycine [INN-French]; Tobramycinum [INN-Latin]; Tobrex (TN); Tobramycin (JP15/USP); Tobramycin[USAN:BAN:INN:JAN]; TOA-(1-6)2TB-(4-1)TOC; TOA-(1-6)TOB-(4-1)TOC; 1-Epitobramycin; 3'-Deoxykanamycin B
Indication
Disease Entry ICD 11 Status REF
Bacteremia 1A73 Approved [1]
Bacterial infection 1A00-1C4Z Approved [2]
Blepharoconjunctivitis N.A. Approved [1]
Corneal abrasion NA06.4 Approved [1]
Dacryocystitis N.A. Approved [1]
Demodex blepharitis 1G07 Approved [1]
Neonatal sepsis N.A. Approved [1]
Peritonitis N.A. Approved [1]
Rosacea ED90.0 Approved [1]
Staphylococcal pneumonia N.A. Approved [1]
Staphylococcus aureus infection N.A. Approved [1]
⏷ Show the Full List of Indication(s)
Therapeutic Class
Antibiotics
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

5 Clinical Trial Drug Combination(s) Consisting of This drug
DrugCom Name DrugCom ID Component Drug Indication REF
Ceftazidime + Tobramycin DC69BGG Ceftazidime Cystic Fibrosis [3]
Fluorometholone + Tobramycin DCCY14E Fluorometholone Corneal Ulcer [4]
Tobramycin + Aciclovir DC1AOQH Aciclovir Corneal Ulcer [4]
Azithromycin + Tobramycin DCKBV2P Azithromycin Cystic Fibrosis [5]
Vancomycin + Tobramycin DCJKM5T Vancomycin Surgical Site Infection [6]
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References

1 Tobramycin FDA Label
2 How many modes of action should an antibiotic have Curr Opin Pharmacol. 2008 Oct;8(5):564-73.
3 ClinicalTrials.gov (NCT02526004) Cystic Fibrosis Microbiome-determined Antibiotic Therapy Trial in Exacerbations: Results Stratified
4 ClinicalTrials.gov (NCT05313828) Effect of Various Treatment Modalities on Dendritic Vial Ulcer
5 ClinicalTrials.gov (NCT02677701) Testing the Effect of Adding Chronic Oral Azithromycin to Inhaled Tobramycin in People With Cystic Fibrosis (CF)
6 ClinicalTrials.gov (NCT03308253) Study for Antibiotic Impregnated Calcium Sulfate Beads as Prophylaxis for Surgical Site Infection