Details of the Drug Combinations

General Information of This Drug (ID: DMY9P6E)

Drug Name

calindol DMY9P6E

Synonyms

calindol; CHEMBL2092942; Clindol; GTPL719; SCHEMBL4103949; CHEMBL1801356; ZINC1494434; BDBM50404271; NCGC00344505-01

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]
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Drug Type

Small molecular drug

Structure

3D MOL is unavailable

2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

5 Investigative Drug Combination(s) Consisting of This drug

Normalized Drug Combination Synergy Score

Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Calindol + Trametinib	DC0ZCGP	Trametinib	DD2 (Cell Line: DD2)	[2]
Calindol + Carfilzomib	DC8RM10	Carfilzomib	DD2 (Cell Line: DD2)	[2]
Calindol + GSK2126458	DC06BXJ	GSK2126458	DD2 (Cell Line: DD2)	[2]
Chloroquine + Calindol	DCWGEIC	Chloroquine	Hepatoblastoma (Cell Line: HB3)	[2]
Piperaquine + Calindol	DC618K3	Piperaquine	DD2 (Cell Line: DD2)	[2]
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References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 719).
2	Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.