Details of the Drug Combinations

General Information of This Drug (ID: DMYGHX5)

Drug Name

Moxidectin DMYGHX5

Synonyms

Moxidectin; ProHeart 6; UNII-NGU5H31YO9; Cydectin; NGU5H31YO9; Moxidectine [INN-French]; Moxidectinum [INN-Latin]; Moxidectina [INN-Spanish]; C37H53NO8; Moxidectina; Moxidectine; Moxidectinum; Moxidectin [USAN:INN:BAN]

Indication

Disease Entry	ICD 11	Status	REF
Onchocerciasis	1F6A	Approved	[1]
River blindness	1F6A.0	Approved	[2]
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Structure

3D MOL

2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

3 Clinical Trial Drug Combination(s) Consisting of This drug

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Diethylcarbamazine + Moxidectin	DCXL8IX	Diethylcarbamazine	Lymphatic Filariasis	[3]
Moxidectin + Albendazole	DCDFVQA	Albendazole	Lymphatic Filariasis	[3]
Moxidectin + Albendazole	DCYNMAD	Albendazole	Onchocerciasis	[4]
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References

1	FDA Approved Drug Products from FDA Official Website. 2018. Application Number: (ANDA) 210867.
2	2018 FDA drug approvals.Nat Rev Drug Discov. 2019 Feb;18(2):85-89.
3	ClinicalTrials.gov (NCT04410406) Moxidectin for LF, Cote d'Ivoire (DOLF)
4	ClinicalTrials.gov (NCT04311671) Safety of a Single Dose of Moxidectin Compared With Ivermectin in Individuals Living in Onchocerciasis Endemic Areas and in Individuals Living in Onchocerciasis Endemic Areas With High Levels of Lymphatic Filariasis Co-endemicity Receiving Concomitant Albendazole