Details of the Drug Combinations

General Information of This Drug (ID: DMYLVQF)

Drug Name

indirubin deriv. 8a DMYLVQF

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]
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Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

1 Investigative Drug Combination(s) Consisting of This drug

Normalized Drug Combination Synergy Score

Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Indirubin deriv. 8a + Ruxolitinib	DCVB216	Ruxolitinib	Hodgkin lymphoma (Cell Line: L-1236)	[2]
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References

1	Structural basis for the synthesis of indirubins as potent and selective inhibitors of glycogen synthase kinase-3 and cyclin-dependent kinases. J Med Chem. 2004 Feb 12;47(4):935-46.
2	CheMBL Affinity Phenotypic Cellular Interaction Assay ID: CHEMBL1125976