Details of the Drug Combinations

General Information of This Drug (ID: DMYTE6L)

Drug Name
Enoxacin   DMYTE6L
Synonyms
Almitil; Bactidan; Comprecin; Enoram; Enoxacine; Enoxacino; Enoxacinum; Enoxin; Enoxor; Flumark; Penetrex; Enoxacin Sesquihydrate; Enoxacine [French]; Enoxacino [Spanish]; Enoxacinum [Latin]; Faulding Brand of Enoxacin; Pierre Fabre Brand of Enoxacin Sesquihydrate; Rhone Poulenc Rorer Brand of Enoxacin Sesquihydrate; AT 2266; AT2266; CI919; CL23362; E0762; PD 107779; PD107779; AT-2266; Almitil (TN); Bactidan (TN); Bactidron (TN); Comprecin (TN); Enoksetin (TN); Enoxen (TN); Enoxin (TN); Enoxor (TN); Enroxil (TN); Flumark (TN); Gyramid (TN); PD-107779; Penetrex (TN); Rhone-Poulenc Rorer Brand of Enoxacin Sesquihydrate; Sesquihydrate, Enoxacin; Vinone (TN); Enoxacin (USAN/INN); Enoxacin [USAN:BAN:INN:JAN]; 1,8-Naphthyridine-3-carboxylic acid, 6-fluoro-1,4-dihydro-4-oxo-7-piperazinyl; 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-1,8-naphthyridine-3-carboxylic acid; 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-[1-piperazinyl]-1,8-naphthyridine-3-carboxylic acid; 1-Ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid; 1-ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid; 1-ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid; 1-ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,8-naphthyridine-3-carboxylic acid
Indication
Disease Entry ICD 11 Status REF
Acute gonococcal cervicitis N.A. Approved [1]
Urinary tract infection GC08 Approved [2]
Therapeutic Class
Antiinfective Agents
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

52 Investigative Drug Combination(s) Consisting of This drug
Normalized Drug Combination Synergy Score
Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.
DrugCom Name DrugCom ID Component Drug Indication REF
Acetazolamide + Enoxacin DCKR3UJ Acetazolamide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Acetohydroxamic Acid + Enoxacin DCGZC2M Acetohydroxamic Acid Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Amodiaquine + Enoxacin DCVT146 Amodiaquine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Arfolitixorin + Enoxacin DC3EBFZ Arfolitixorin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Armodafinil + Enoxacin DCRRUSV Armodafinil Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Artemisinin + Enoxacin DC9RJBV Artemisinin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Asenapine + Enoxacin DCV85TU Asenapine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Auranofin + Enoxacin DC8XOTZ Auranofin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
BHV-0223 + Enoxacin DCMUTEJ BHV-0223 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Cerivastatin + Enoxacin DCHVKXP Cerivastatin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Cilostazol + Enoxacin DCGZVQJ Cilostazol Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Cytarabine + Enoxacin DCL8J05 Cytarabine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Darunavir + Enoxacin DCTS9KA Darunavir Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Dexmedetomidine + Enoxacin DCY4D2N Dexmedetomidine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Dextromethorphan + Enoxacin DCT5ICD Dextromethorphan Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Dihydroergotamine + Enoxacin DCGRIKW Dihydroergotamine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Docetaxel + Enoxacin DC360F8 Docetaxel Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Emetine + Enoxacin DCGIQ5C Emetine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Enoxacin + Gefitinib DC9WGHJ Gefitinib Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Enoxacin + Diethylcarbamazine DC2SH03 Diethylcarbamazine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Enoxacin + Tacrine DCV73W3 Tacrine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Enoxacin + Anamorelin DC55IMS Anamorelin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Enoxacin + Triapine DCBX6IG Triapine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Enoxacin + Metyrosine DCLMR8N Metyrosine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Enoxacin + Sulfapyridine DC8LWHM Sulfapyridine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Enoxacin + BIO-300 DCIW6WG BIO-300 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Enoxacin + Idarubicin DC5TQ0C Idarubicin Glioblastoma? (Cell Line: T98G) [3]
Enoxacin + Methylene blue DCMQRPC Methylene blue Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Enoxacin + Brincidofovir DCIK1ZN Brincidofovir Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Enoxacin + Mycophenolic acid DCQ0F8M Mycophenolic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Enoxacin + Doxorubicin DCX1H12 Doxorubicin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Etonogestrel + Enoxacin DC8WM99 Etonogestrel Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
GS4071 + Enoxacin DC62ZFQ GS4071 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Hyodeoxycholic acid + Enoxacin DCF5QJD Hyodeoxycholic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Imatinib + Enoxacin DC8RZDU Imatinib Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Itraconazole + Enoxacin DCGAQ2A Itraconazole Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Kanamycin + Enoxacin DC0KZ2P Kanamycin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Mefloquine + Enoxacin DCLJ4W0 Mefloquine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Niclosamide + Enoxacin DCX0BZJ Niclosamide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Novobiocin + Enoxacin DC2E7BR Novobiocin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Oxyphenbutazone + Enoxacin DCWBCCS Oxyphenbutazone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Pinacidil + Enoxacin DC4IQ7C Pinacidil Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
PMID28460551-Compound-2 + Enoxacin DCBWQZE PMID28460551-Compound-2 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Ramelteon + Enoxacin DCEYDUA Ramelteon Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Tamoxifen + Enoxacin DCGJ7Z3 Tamoxifen Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Testosterone cypionate + Enoxacin DC2WKYV Testosterone cypionate Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Tiagabine + Enoxacin DCLLPLN Tiagabine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Topotecan + Enoxacin DC0MZ06 Topotecan Chronic myelogenous leukemia (Cell Line: KBM-7) [4]
Tranexamic acid + Enoxacin DC1WZL2 Tranexamic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Trimethobenzamide + Enoxacin DCD04D2 Trimethobenzamide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Vinblastine + Enoxacin DCCB2QS Vinblastine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
WAY-100635 + Enoxacin DC8ZXO7 WAY-100635 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
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⏷ Show the Full List of 52 DrugCom(s)

References

1 Enoxacin FDA Label
2 FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 019616.
3 Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.
4 Loss of function mutations in VARS encoding cytoplasmic valyl-tRNA synthetase cause microcephaly, seizures, and progressive cerebral atrophy.Hum Genet. 2018 Apr;137(4):293-303. doi: 10.1007/s00439-018-1882-3. Epub 2018 Apr 24.