Details of the Drug Formulations

General Information of Drug (ID: DM2TEOL)

Drug Name
Methotrexate Drug Info
Synonyms
methotrexate; 1959/5/2; Rheumatrex; Amethopterin; Metatrexan; Hdmtx; Abitrexate; Mexate; Methylaminopterinum; Methotrexatum; Antifolan; Metotrexato; Methylaminopterin; MTX; (S)-2-(4-(((2,4-Diaminopteridin-6-yl)methyl)(methyl)amino)benzamido)pentanedioic acid; Methotrexat; Amethopterine; Maxtrex; Rasuvo; L-Amethopterin; A-Methopterin; A-Methpterin; Amethopterin L-; Folex-Pfs; Methotrexat-Ebewe; N-Bismethylpteroylglutamic acid; Methotrexate, L-; Metotressato [DCIT]; Methotextrate; Mexate-Aq; [3H]methotrexate
Indication
Disease Entry ICD 11 Status REF
Anterior urethra cancer Approved [1]
Burkitt lymphoma Approved [1]
Childhood acute lymphoblastic leukemia Approved [1]
Choriocarcinoma 2C75.0 Approved [2]
Gestational trophoblastic neoplasia 2F33-2F76 Approved [1]
Head and neck cancer 2D42 Approved [1]
Inflammation 1A00-CA43.1 Approved [1]
leukaemia 2A60-2B33 Approved [3]
Leukemia Approved [1]
Lung cancer 2C25.0 Approved [1]
Mycosis fungoides 2B01 Approved [1]
Posterior urethra cancer Approved [1]
Psoriasis EA90 Approved [1]
Sensorineural hearing loss disorder Approved [1]
Urticaria EB00-EB05 Approved [1]
Proliferative vitreoretinopathy 9B78.2 Phase 3 [4]
Solid tumour/cancer 2A00-2F9Z Phase 3 [3]
Coronavirus Disease 2019 (COVID-19) 1D6Y Phase 1/2 [5]
Rheumatoid arthritis FA20 Phase 1 [6]
Prostate cancer 2C82.0 Investigative [7]
Cross-matching ID
PubChem CID
126941
ChEBI ID
CHEBI:44185
CAS Number
59-05-2
TTD ID
D0SV8E
VARIDT ID
DR00082
INTEDE ID
DR1045
ACDINA ID
D00412

Full List of Drug Formulations Containing This Drug

Methotrexate 15 mg tablet
Company Formulation ID FDA Description
Teva Women's Health F13481 Anhydrous lactose; Fd&c red no. 40; Fd&c blue no. 2; Indigotindisulfonate sodium; Magnesium stearate; Sodium carbonate monohydrate; Talc; Titanium dioxide; Polyethylene glycol 400; Polysorbate 80; Cellulose, microcrystalline; Crospovidone (15 mpa.s at 5%); Hypromellose 2910 (3 mpa.s); Hypromellose 2910 (6 mpa.s); Starch, corn
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Methotrexate 5 mg tablet
Company Formulation ID FDA Description
Teva Women's Health F13494 Anhydrous lactose; D&c yellow no. 10; Fd&c blue no. 1; Fd&c yellow no. 6; Magnesium stearate; Sodium carbonate monohydrate; Talc; Titanium dioxide; Polyethylene glycol 400; Polysorbate 80; Cellulose, microcrystalline; Crospovidone (15 mpa.s at 5%); Hypromellose 2910 (3 mpa.s); Hypromellose 2910 (6 mpa.s); Starch, corn
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Methotrexate 10 mg tablet
Company Formulation ID FDA Description
Teva Women's Health F13480 Anhydrous lactose; Fd&c red no. 40; Magnesium stearate; Sodium carbonate monohydrate; Talc; Titanium dioxide; Polyethylene glycol 400; Polysorbate 80; Cellulose, microcrystalline; Crospovidone (15 mpa.s at 5%); Hypromellose 2910 (3 mpa.s); Hypromellose 2910 (6 mpa.s); Starch, corn
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Methotrexate 7.5 mg tablet
Company Formulation ID FDA Description
Teva Women's Health F13495 Anhydrous lactose; Fd&c blue no. 1; Magnesium stearate; Sodium carbonate monohydrate; Talc; Titanium dioxide; Polyethylene glycol 400; Polysorbate 80; Cellulose, microcrystalline; Crospovidone (15 mpa.s at 5%); Hypromellose 2910 (3 mpa.s); Hypromellose 2910 (6 mpa.s); Starch, corn
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Methotrexate 2.5 mg tablet
Company Formulation ID FDA Description
Mylan Pharamceuticals F13493 Lactose monohydrate; Sodium lauryl sulfate; Fd&c red no. 40; Magnesium stearate; Sodium carbonate monohydrate; Silicon dioxide; Cellulose, microcrystalline; Sodium starch glycolate type a potato; Starch, corn
Physicians Total Care F13483 Anhydrous lactose; Magnesium stearate; Propylene glycol; Sodium carbonate monohydrate; Talc; Cellulose, microcrystalline; Polyethylene glycol; Starch, corn
Rebel Distributors F13485 Anhydrous lactose; Magnesium stearate; Propylene glycol; Sodium carbonate monohydrate; Talc; Cellulose, microcrystalline; Hypromellose 2208 (100000 mpa.s); Polyethylene glycol; Starch, corn
RemedyRepack F13486 Anhydrous lactose; Magnesium stearate; Propylene glycol; Sodium carbonate monohydrate; Talc; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycol; Starch, corn
RemedyRepack F13487 Anhydrous lactose; Magnesium stearate; Propylene glycol; Sodium carbonate monohydrate; Talc; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycol; Starch, corn
A-S Medication Solutions; AvKARE; Barr Laboratories; PD-Rx Pharmaceuticals F13488 Anhydrous lactose; Magnesium stearate; Propylene glycol; Sodium carbonate monohydrate; Talc; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols; Starch, corn
Cadila Healthcare; Zydus Pharmaceuticals F13482 Anhydrous lactose; Lactose monohydrate; Magnesium stearate; Cellulose, microcrystalline; Starch, pregelatinized corn
Bryant Ranch Prepack; West-Ward Pharmaceticals F13484 Anhydrous lactose; Magnesium stearate; Sodium hydroxide; Sodium starch glycolate type a potato; Starch, corn
Dispensing Solution; GenPak Solutions; Major Pharmaceuticals; Rebel Distributors F13489 Lactose; Magnesium stearate; Starch, corn
RemedyRepack F13490 Lactose monohydrate; Magnesium stearate; Starch, corn
Sun Pharmaceutical Industries F13491 Lactose monohydrate; Magnesium stearate; Microcrystalline cellulose
A-S Medication Solutions; DAVA Pharmaceuticals; PD-Rx Pharmaceuticals; RemedyRepack F13492 Lactose monohydrate; Magnesium stearate; Starch, corn
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⏷ Show the Full List of 12 Formulation(s)
Methotrexate Sodium 2.5mg tablet
Company Formulation ID FDA Description
Sun Pharmaceutical Industries F23483 Lactose Monohydrate; Microcrystalline Cellulose; Magnesium Stearate
Bryant Ranch Prepack F23481 Anhydrous Lactose; Magnesium Stearate; Starch, Corn
Avkare F23482 Lactose Monohydrate; Magnesium Stearate; Starch, Corn
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References

1 Methotrexate FDA Label
2 FDA Approved Drug Products from FDA Official Website. 2019. Application Number: (ANDA) 040632.
3 Pain reduction with oral methotrexate in knee osteoarthritis, a pragmatic phase iii trial of treatment effectiveness (PROMOTE): study protocol for ... Trials. 2015 Mar 4;16:77.
4 ClinicalTrials.gov (NCT04136366) The GUARD Trial - Part 1: A Phase 3 Clinical Trial for Prevention of Proliferative Vitreoretinopathy. U.S. National Institutes of Health.
5 ClinicalTrials.gov (NCT04352465) Efficacy and Safety of MTX-loaded Nanoparticles to Treat Severe COVID-19 Patients. U.S. National Institutes of Health.
6 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800034238)
7 The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954.